This paper presents a study on the formability prediction, thickness variation, the influence of the gradient temperature, and prediction damage and failure behavior of aluminum sheets in a hydroforming vapor process through experimental and numerical investigations. A vapor hydroforming process that takes advantage of the coupling between thermal and mechanical loads applied to sheet metal is introduced. Uniaxial tensile tests and an optimization program developed in Matlab and based on the inverse method were conducted for identifying the coefficients of the Johnson-Cook law at room and at different temperatures. In parallel, a finite element model of the hydroforming vapor process was developed using ABAQUS/Explicit to reproduce the behavior of the aluminum sheet, where the behavior of the coupled thermo viscoelastic material and to the damage prediction of the plate being tested is analyzed using Johnson-Cook model. The results confirm the feasibility of the forming process. The variation of sheet thickness, the thinning mode of the tested sheet, and the effects of the hydroforming temperature are studied. A good agreement was achieved between experimental data and numerical results.