On-farm varietal trial was carried out to evaluate promising genotypes of potato received from International Potato Centre (CIP), Lima, Peru through National Potato Research Program (NPRP), Khumaltar at Guthichaur Rural Municipality in the high hills of Jumla during two consecutive years 2017 and 2018. Five promising potato genotypes and two check cultivars i.e. Desiree and Jumli Local were tested in Randomized Complete Block Design (RCBD). The treatments were replicated three times. Compost was used at the rate of 20 t/ha. Well sprouted tubers of 25-50 g were planted at 60cm x 25cm spacing. Observations were recorded on vegetative parameters and yield attributes. Tested genotypes differed significantly for emergence percentage at 30 days after planting, uniformity, ground coverage, plant height, number of main stems, total number of tubers and tuber yield per hectare. The highest tuber yield (26.14 t/ha) was recorded in CIP393073.179 followed by CIP 395112.32 (24.56 t/ha) and CIP 390478.9 (23.12 t/ha). The average results of both years showed that potato genotypes CIP393073.179, CIP 395112.32 and CIP 390478.9 were promising for commercial cultivation in Jumla and in the similar agro-ecological domains of Karnali province.