Analysis of 107 breast lesions with automated 3D ultrasound and comparison with mammography and manual ultrasound

Kotsianos-Hermle, D.; Hiltawsky, K.M.; Wirth, Stéfan; Fischer, T.; Friese, K.; Reiser, Maximilian

doi:10.1016/j.ejrad.2008.04.001

Cited by 70 publications

(23 citation statements)

References 15 publications

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“…A review of coronal images may be helpful for distinguishing between real lesions and non-homogeneous areas [16]. Several studies have suggested that the retraction phenomenon with an irregular margin on the coronal plane is a characteristic of breast cancer [8,17,18], and lobular carcinoma presents an architectural distortion on the coronal plane images that is not apparent when using mammography or conventional 2D ultrasonography [18,19]. Additionally, a multislice observation of ABUS images leads to a more consistent interpretation of the lesion margin than a static HHUS image [11].…”

Section: Discussionmentioning

confidence: 99%

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Interobserver agreement on the interpretation of automated whole breast ultrasonography

Kim

Kang

et al. 2014

Ultrasonography

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Purpose:The purpose of this study was to prospectively evaluate the interobserver agreement on lesion characterization and the final assessment of automated whole breast ultrasonography (ABUS) images.Methods:Between March and August 2012, 172 women underwent bilateral ABUS before biopsy guided by handheld ultrasonography (HHUS) and mammography. A total of 206 breast lesions were confirmed histopathologically by biopsy. Three-dimensional volume data from ABUS scans were analyzed by two radiologists without the knowledge of HHUS results or patient clinical information. The two readers described the type, shape, orientation, margin, echogenicity, posterior acoustic features, and categorization of the final assessment of detected breast lesions. Kappa statistics were used to analyze the described characteristics of the breast lesions detected by both of the two readers.Results:Of the 206 histopathologically confirmed lesions, reader 1 detected 166 lesions and reader 2 detected 150 lesions. A total of 145 lesions were detected by both readers using ABUS images. There was substantial agreement on shape (κ=0.707), and moderate agreement on type, margin, mass orientation, echogenicity, and posterior acoustic features (κ=0.592, 0.438, 0.472, 0.524, and 0.541, respectively). Breast Imaging Reporting and Data System final assessment values yielded a kappa value of 0.3971 when category subdivisions 4A, 4B, and 4C were included. With respect to the C2, C3, C4, and C5 categories, the interobserver agreement was moderate (κ=0.505).Conclusion:ABUS is a promising diagnostic tool with a good interobserver agreement, comparable to that of HHUS.

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Section: Discussionmentioning

confidence: 99%

“…To improve upon these problems, a new approach, the automated breast ultrasonography, has been developed [8,9]. Automated whole breast ultrasonography (ABUS) scans the entire breast in a standardized manner and sends all resulting images to a workstation [10].…”

Section: Introductionmentioning

confidence: 99%

Interobserver agreement on the interpretation of automated whole breast ultrasonography

Kim

Kang

et al. 2014

Ultrasonography

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“…For the HHUS examinations, a sensitivity of 81-100% and a specificity of 33-88% have been reported to detect malignant and benign lesions (7, 11, 12). For the AWUS examinations, two studies reported that the sensitivity was 71.9% (5) and 96.5% (7), respectively, and the specificity was 74.5% (5) and 92.3% (7), respectively.…”

Section: Discussionmentioning

confidence: 99%

“…Nevertheless, the current high-resolution AWUS scanners with volumetric technologies can demonstrate the breast anatomy and document the breast lesions more accurately (1). Several studies have shown the good diagnostic performance (4-7) and good interobserver agreement (6, 7) between the volumetric AWUS and the HHUS. As good interobserver variability of using American College of Radiology (ACR) breast imaging reporting and data system lexicon and excellent expected malignancy probability of ACR BI-RADS assessment has been proved in HHUS, that of AWUS needs to be evaluated in advance for clinical application of screening or diagnostic setting.…”

Section: Introductionmentioning

confidence: 99%

Radiologists' Performance for Detecting Lesions and the Interobserver Variability of Automated Whole Breast Ultrasound

et al. 2013

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ObjectiveTo compare the detection performance of the automated whole breast ultrasound (AWUS) with that of the hand-held breast ultrasound (HHUS) and to evaluate the interobserver variability in the interpretation of the AWUS.Materials and MethodsAWUS was performed in 38 breast cancer patients. A total of 66 lesions were included: 38 breast cancers, 12 additional malignancies and 16 benign lesions. Three breast radiologists independently reviewed the AWUS data and analyzed the breast lesions according to the BI-RADS classification.ResultsThe detection rate of malignancies was 98.0% for HHUS and 90.0%, 88.0% and 96.0% for the three readers of the AWUS. The sensitivity and the specificity were 98.0% and 62.5% in HHUS, 90.0% and 87.5% for reader 1, 88.0% and 81.3% for reader 2, and 96.0% and 93.8% for reader 3, in AWUS. There was no significant difference in the radiologists' detection performance, sensitivity and specificity (p > 0.05) between the two modalities. The interobserver agreement was fair to good for the ultrasonographic features, categorization, size, and the location of breast masses.ConclusionAWUS is thought to be useful for detecting breast lesions. In comparison with HHUS, AWUS shows no significant difference in the detection rate, sensitivity and the specificity, with high degrees of interobserver agreement.

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“…Several studies have concluded that the sensitivity, diagnostic performances, and image quality of AWUS and HHUS are equivalent [15161718192021]. However, these studies have primarily evaluated mass lesions in the breast.…”

Section: Introductionmentioning

confidence: 99%

Detectability and Usefulness of Automated Whole Breast Ultrasound in Patients with Suspicious Microcalcifications on Mammography: Comparison with Handheld Breast Ultrasound

et al. 2016

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PurposeThe purpose of this study was to prospectively evaluate the detectability and usefulness of automated whole breast ultrasound (AWUS) and to compare it with handheld breast ultrasound (HHUS) in cases with suspicious microcalcifications identified by mammography.MethodsForty-two patients with 43 suspicious microcalcifications (25 malignant and 18 benign) detected by mammography underwent AWUS, HHUS, and histol-ogic examination. With knowledge of the mammographic findings, HHUS was performed to assess the visibility of the microcalcifications and the presence of associated masses or ductal changes. Two radiologists reviewed the AWUS images in consensus using the same methods employed for HHUS. Detectability of AWUS was compared with that of HHUS and was correlated with histologic and mammographic findings.ResultsOf the 43 lesions, 32 (74.4%) were detectable by AWUS and 31 (72.1%) by HHUS. No significant differences in sensitivity were found between the two methods (p=0.998). AWUS detected 96% (24/25) of malignant microcalcifications and 44.4% (8/18) of benign microcalcifications. AWUS was more successful in the detection of malignant vs. benign lesions (96.0% vs. 44.4%, p=0.002), lesions >10 mm vs. ≤10 mm in size (86.7% [26/30] vs. 46.2% [6/13], p=0.009), lesions with a fine pleomorphic or linear shape vs. a round or amorphous or coarse heterogeneous shape (94.7% [18/19] vs. 58.3% [14/24], p=0.021), and lesions associated with a mass or architectural distortion vs. without obvious changes on mammography (100% [19/19] vs. 54.2% [13/24], p=0.022).ConclusionDetectability of AWUS was comparable to that of HHUS in cases where suspicious microcalcifications were identified on mammography. Therefore, AWUS might be helpful in the performance of ultrasound-guided percutaneous procedures for highly suspicious microcalcifications.

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Analysis of 107 breast lesions with automated 3D ultrasound and comparison with mammography and manual ultrasound

Cited by 70 publications

References 15 publications

Interobserver agreement on the interpretation of automated whole breast ultrasonography

Interobserver agreement on the interpretation of automated whole breast ultrasonography

Radiologists' Performance for Detecting Lesions and the Interobserver Variability of Automated Whole Breast Ultrasound

Detectability and Usefulness of Automated Whole Breast Ultrasound in Patients with Suspicious Microcalcifications on Mammography: Comparison with Handheld Breast Ultrasound

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