Analysis of 118 Pesticides in Tobacco after Extraction With the Modified QuEChRS Method by LC–MS-MS

Abstract

A liquid chromatography-tandem quadrupole mass spectrometry (LC-MS-MS) multi-residue method for the simultaneous target analysis of a wide range of pesticides in tobacco has been developed. Gradient elution has been used in conjunction with positive mode electrospray ionization tandem mass spectrometry to detect up to 118 pesticides in tobacco. The recoveries obtained for each pesticide ranged between 70 and 118% at two spiked concentration levels. Good linear relationships were observed with correlation coefficients r(2) > 0.992 for all analytes. The established method was successfully applied to the determination of pesticide residues in real tobacco samples in order to validate the suitability for routine analysis.

Ultra‐performance convergence chromatography with tandem mass spectrometry‐assisted method for rapid enantioseparation and determination of fluazifop‐butyl in tobacco and soil

“…21 The main steps are reported below: Weigh 2 g of the dried sample into a 50-mL centrifuge tube, add 10 mL of ultrapure water and 10 mL of acetonitrile, and vortex for 2 minutes. Five soil samples were also from the above five regions.…”

“…QuEChERS was adopted as sample preparation, whose operation procedures were similar to the previous research of the authors. 21 The main steps are reported below: Weigh 2 g of the dried sample into a 50-mL centrifuge tube, add 10 mL of ultrapure water and 10 mL of acetonitrile, and vortex for 2 minutes. Then, 4-g MgSO 4 and 1-g NaCl were added and continued to vortex for another 2 minutes; 1.0 mL of the supernatant was pipetted into a 2-mL centrifuge tube containing 25 mg of PSA adsorbent and 150 mg of anhydrous MgSO 4 .…”

Validated analytical methodology for the simultaneous determination of a wide range of pesticides in human blood using GC–MS/MS and LC–ESI/MS/MS and its application in two poisoning cases

“…The use of any of these analytical techniques is currently seen as a practical way to overcome the difficulties posed by complex biological matrices, which may contain an excessive amount of potentially interfering substances, such as fat, protein, sugars, and chemicals [7]. In addition, high acquisition speed in the MRM mode allows the development of methods for the simultaneous analysis of tens or even hundreds of compounds belonging to different chemical classes [8][9][10][11][12].…”

Magnetic graphene as modified quick, easy, cheap, effective, rugged and safe adsorbent for the determination of organochlorine pesticide residues in tobacco

“…In recent years, the widespread presence of pesticide residues in agricultural products such as tobacco has attracted considerable public attention because of their potential risks to human health, animals and environment [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15]. For this reason, the pesticide residues in tobacco should be monitored to protect the consumer.…”