Analysis of 1246 Cases of Orbital Lesions: A Study of 17 Years

Abstract

Purpose: The aim of this study is to present an analysis of orbital lesions by classifying them according to the site of origin in patients of all ages presenting at a tertiary care eye hospital from 1996 till 2012. Methods: 1637 patients were initially enrolled in this descriptive case series. Clinical data of 1246 patients who completed the study during 17 years were analyzed. Orbital lesions of the patients were examined and managed medically or surgically as per requirement. The histopathological reports of these patients were used to classify the lesions. Results: Out of all cases 54.57% (n = 680) were neoplastic and 45.42% (n = 566) were nonneoplastic lesions. Amongst the neoplastic lesions 86.17% (n = 586) were malignant and 13.82% (n = 94) were benign. Primary orbital lesions were the most common orbital lesions being 963 (77.29%) followed by secondary orbital lesions being 232 (18.62%), hematopoietic reticuloendothelial being 47 (3.77%) and metastatic lesions being 04 (0.32%). Conclusion: Orbital lesions are more common in adults as compared to children. Neoplastic lesions are more common than nonneoplastic lesions, and amongst the neoplastic lesions malignant lesions are more common than benign ones. Primary orbital lesions are the most common orbital lesions followed by secondary orbital lesions, lesions of the hematopoietic reticuloendothelial system and metastatic lesions.

Demographic Distribution of Oculoplastic Disorders in Port Harcourt Nigeria

“…This was similar to the study by Balogun et al one of the peak age groups was 20 This was however different from the findings by Anunobi et al [2] with 51.1% of cases b children under 15 years old and those of Bekibele [3] in Ibadan, Nigeria with 50% of children and young adults from 0 to 20 years old. It was also at variance with the findings of Asad Aslam Khan et al [4] who predominance of adults with 57.47% of cases in Age distribution of oculoplastic disorders group in our study was 21-30 years and followed by 31 to 40 years. This was similar to the study by Balogun et al [1] where one of the peak age groups was 20-29 years.…”

“…In a similar study by Bekibele et al in Ibadan Nigeria, 50% of cases were children and young adults from 0 to 20 years old [3]. However in a study in Pakistan, Asad Aslam Khan et al observed a predominance of adults with 57.47% of cases [4] while Balogun etal had two peak age groups of 0-9 years (22.7%) and 20-29 years (19.3%) [1].…”

Single Institutional Experience in Surgical Management of Orbital Tumoursneurosurgical Perspective in Surgical Approach

“…Procedures that can be performed will range from simple biopsy to near total or total resection depending on the histological variant. 3,4,5 Most appropriate surgical approach chosen for making complete excision possible. Approaches can be divided into transorbital and extra-orbital approaches.…”

“…1 These tumours include tumours of lacrimal gland, adipose tissue, fibrous tissue, muscle tissue, bone and cartilage, tumours of blood vessels and lymphatics, tumours of peripheral nerves and cranial nerves, tumours of optic nerve, tumours of dural meninges, arachnoid and metastasis from adjacent or distant site. 1,2,3,4 Orbital tumours present with visual disturbances as decreased vision and double vision, proptosis, periorbital and retro-orbital pain, lacrimation, conjunctival oedema and inflammation. 3,4 Many neoplastic conditions masquerade as or mimic other less aggressive inflammatory conditions and should be differentiated before definitive therapy is planned.…”

“…1,2,3,4 Orbital tumours present with visual disturbances as decreased vision and double vision, proptosis, periorbital and retro-orbital pain, lacrimation, conjunctival oedema and inflammation. 3,4 Many neoplastic conditions masquerade as or mimic other less aggressive inflammatory conditions and should be differentiated before definitive therapy is planned. Clinical examination and radiological investigations are not so helpful in preoperative diagnosis in all cases of orbital tumours.…”