Analysis of 24 cases of polycystic ovary syndrome after failed controlled ovarian hyperstimulation

Li, Donghong; Guo, Yujia; Lu, S; Zhong, Yao; Zhu, Wenbing; Liu, Qicai

doi:10.7861/clinmedicine.19-4-348

Cited by 2 publications

(2 citation statements)

References 12 publications

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“…PCOS is a complex endocrine and metabolic disorder in women of childbearing age, with a prevalence of 4-21% [25]. IVF-ET is a common pregnancy assistance treatment for infertile PCOS patients [26]. Many infertile patients with PCOS administered an IVF-ET cycle can achieve a pregnancy [27].…”

Section: Discussionmentioning

confidence: 99%

The effects of Chinese herbal medicine on the pregnancy outcomes of infertile women with polycystic ovary syndrome undergoing in vitro fertilization-embryo transfer: a systematic review and meta-analysis

Liu,

Dai,

Zhao

et al. 2021

Clin. Exp. Obstet. Gynecol.

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Background: At present, Chinese herbal medicine (CHM) has already been widely used as an important adjuvant treatment for polycystic ovary syndrome (PCOS) patients undergoing in vitro fertilizationembryo transfer (IVF-ET). This systematic review and meta-analysis were designed to evaluate the effects of CHM on the pregnancy outcomes of infertile women with PCOS undergoing IVF-ET. Methods: We searched seven electronic databases systematically for published articles to January 2021. All randomized controlled trials (RCTs) comparing CHM with blank or placebo for infertile PCOS patients undergoing IVF-ET were included. The measures of treatment effect were the pooled odds ratios (OR) of the clinical pregnancy rate, the abortion rate and the ovarian hyperstimulation syndrome (OHSS) incidence. Results: This meta-analysis included 10 studies involving 663 patients comparing CHM with blank or placebo for infertile PCOS patients undergoing IVF-ET. The pooled data showed that CHM could improve the clinical pregnancy rate (OR = 2.41, 95% CI: 1.73-3.35, p < 0.01) and reduce the OHSS incidence (OR = 0.31, 95% CI: 0.18-0.55, p < 0.01) of infertile PCOS patients with IVF-ET treatment. No significant difference in the abortion rate was found between the CHM and control groups (OR = 0.64, 95% CI: 0.23-1.81, p = 0.40). Discussion: CHM can be used as an auxiliary treatment for infertile PCOS patients undergoing IVF-ET.

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Section: Discussionmentioning

confidence: 99%

The effects of Chinese herbal medicine on the pregnancy outcomes of infertile women with polycystic ovary syndrome undergoing in vitro fertilization-embryo transfer: a systematic review and meta-analysis

Liu,

Dai,

Zhao

et al. 2021

Clin. Exp. Obstet. Gynecol.

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“…Ovarian hyperstimulation syndrome (OHSS) is a complication sourced by excessive ovulation stimulation that occurs in 1-10% of IVF and embryo transfer cycles (9). Although mild OHSS has no clinical significance, severe OHSS is a life-threatening complication (10).…”

Section: Introductionmentioning

confidence: 99%

The value of ovarian hyperstimulation syndrome in predicting pregnancy outcome in women with polycystic ovarian syndrome and candidate for in vitro fertilization: A case-control study

Pilehvari,

Radnia,

Ahmadiani

et al. 2023

IJRM

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Background: Ovarian hyperstimulation syndrome (OHSS) as a known complication in women with polycystic ovarian syndrome (PCOS) may occur following inducible fertility treatments such as in vitro fertilization (IVF) and can affect the sequels of these treatments. Objective: This study aimed to assess the effects of OHSS on pregnancy outcomes through IVF in women with PCOS. Also, we assessed the value of baseline sexual hormones to predict the pregnancy’s success. Materials and Methods: This case-control study was conducted on 180 consecutive women suffering from PCOS who were candidates for IVF at Fatemieh hospital in Hamadan, Iran, from May-July 2022. The women were assigned to the case group (with OHSS, n = 129) and the control group (without OHSS, n = 51). Measuring the sexual hormones was performed using the enzyme-linked immunosorbent technique. Results: In the multivariable logistic regression model, OHSS could not predict the likelihood of clinical or chemical pregnancy following IVF. None of the baseline sexual hormones could predict the successful chemical or clinical pregnancy in PCOS women following IVF. Conclusion: OHSS may not influence IVF-related outcomes in PCOS women. The values of sexual hormones may not also determine the pointed outcome. Key words: Ovarian hyperstimulation syndrome, Fertilization, Polycystic ovary syndrome.

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Analysis of 24 cases of polycystic ovary syndrome after failed controlled ovarian hyperstimulation

Cited by 2 publications

References 12 publications

The effects of Chinese herbal medicine on the pregnancy outcomes of infertile women with polycystic ovary syndrome undergoing in vitro fertilization-embryo transfer: a systematic review and meta-analysis

The effects of Chinese herbal medicine on the pregnancy outcomes of infertile women with polycystic ovary syndrome undergoing in vitro fertilization-embryo transfer: a systematic review and meta-analysis

The value of ovarian hyperstimulation syndrome in predicting pregnancy outcome in women with polycystic ovarian syndrome and candidate for in vitro fertilization: A case-control study

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