2002
DOI: 10.1016/s1383-5718(01)00288-1
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Analysis of adaptive response to bleomycin and mitomycin C

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Cited by 32 publications
(16 citation statements)
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“…For example, Mahmood et al (1996) reported that in murine cells the AR was induced by the methylating agent methyl methanesulfonate and was stronger than that induced by the ethylating agent ethyl methanesulfonate. Schlade-Bartusiak et al (2002) showed a more pronounced AR in human lymphocytes after treatment with bleomycin, which generates DNA breaks, than with the alkylating agent mitomycin.…”
Section: Molecular Mechanisms Of the Adaptive Responsementioning
confidence: 95%
See 1 more Smart Citation
“…For example, Mahmood et al (1996) reported that in murine cells the AR was induced by the methylating agent methyl methanesulfonate and was stronger than that induced by the ethylating agent ethyl methanesulfonate. Schlade-Bartusiak et al (2002) showed a more pronounced AR in human lymphocytes after treatment with bleomycin, which generates DNA breaks, than with the alkylating agent mitomycin.…”
Section: Molecular Mechanisms Of the Adaptive Responsementioning
confidence: 95%
“…1999; Wang and Cai, 2000;Sawant et al, 2001; Kale, 2001, 2004;Venkat et al, 2001;Assis et al, 2002;Chankova and Bryant, 2002;Gajendiran and Jeevanram, 2002;Rubinelli et al, 2002;Schlade-Bartusiak et al, 2002;Sedgwick and Lindahl, 2002;Jovtchev and Stergios, 2003;Patra et al, 2003;Savina et al, 2003;Ulsh et al, 2004;Zhou et al, 2004;Atanasova et al, 2005;Chankova et al, 2005Chankova et al, , 2007Coleman et al, 2005;Friesner et al, 2005;Lanza et al, 2005;Rohankhedkar et al, 2006;Seo et al, 2006).…”
mentioning
confidence: 99%
“…The AR has been observed in bacteria (Assis et al, 2002;Sedgwick & Lindahl, 2002;Rohankhedkar et al, 2006), yeast (Boreham & Mitchel, 1991;Gajendiran & Jeevanram, 2002), algae (Chankova & Bryant, 2001;Rubinelli et al, 2002;Chankova et al, 2007), insect cells (Savina et al, 2003), mammalian cells (Wang & Cai, 2000;Tiku & Kale, 2001;Ulsh et al, 2004;Zhou et al, 2004), human cells (Schlade-Bartusiak et al, 2002;Atanasova et al, 2005;Coleman et al, 2005;Friesner et al, 2005;Lanza et al, 2005;Seo et al, 2006) and higher plants models (Rieger et al, 1993;Panda et al, 1997;Jovtchev & Stergios, 2003;Patra et al, 2003). A study of the conditions essential for the induction of an adaptive response is of critical importance to understanding the novel biological defense mechanisms against the hazardous effects of radiation.…”
Section: Hormesis and Molecular Mechanisms Of The Adaptive Responsementioning
confidence: 99%
“…Three newly established LCLs (each produced by EBV infection of primary B cells from mixed donors and cultured for less than 3 months) were treated with mitomycin C and melphalan, two unrelated drugs that, like cisplatin, are bifunctional alkylating agents and generate DNA cross-links and adducts (6,15). The same LCLs were also treated with the radiomimetic drug bleomycin or the topoisomerase II inhibitor etoposide, which, like ␥-IR, can induce DSBs (but not crosslinks) in DNA (10).…”
mentioning
confidence: 99%