Analysis of auditory and neurologic effects associated with ventral bulla osteotomy for removal of inflammatory polyps or nasopharyngeal masses in cats

Anders, Brendan B; Hoelzler, Michael G; Scavelli, Thomas D; Fulcher, Ryan P.; Bastian, Richard P.

doi:10.2460/javma.233.4.580

Cited by 32 publications

(19 citation statements)

References 29 publications

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“…More cats had recurrence of aural IP with simple traction (traction performed without curettage of the tympanic cavity) removal versus surgical intervention, a finding consistent with comparisons from previous reports. [19][20][21][22][23] For those cats where recurrence was documented, use of topical and/or systemic glucocorticoids did not seem to have an impact on time to recurrence. A larger sample size may have yielded different results, as several authors 23 have suggested a relationship between glucocorticoid therapy and lack of recurrence of polyps.…”

Section: Discussionmentioning

confidence: 99%

Feline bilateral inflammatory aural polyps: a descriptive retrospective study

Hoppers

May

Frank

2020

Veterinary Dermatology

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Background Feline inflammatory aural polyps (IP) have been reported as solitary growths, yet bilateral polyps may occur more commonly than described previously. Objectives To identify the prevalence and risk factors associated with bilateral feline IP within a population of cats evaluated at a veterinary teaching hospital over a 10 year period. Animals Twenty‐five cats with histologically confirmed IP. Methods and materials A retrospective study was performed by searching computerized medical records of cats seen at The University of Tennessee Veterinary Teaching Hospital from 2005 to 2015. Keywords used for the search included “feline polyp”, “ventral bulla osteotomy”, “inflammatory polyp ear canal” and “nasopharyngeal polyp”. Results Cats were separated into groups with unilateral or bilateral disease. Six of 25 (24%) cats had bilateral IP. Twelve cats had computed tomography performed (four of six with bilateral IP; eight of 19 with unilateral IP). Clinical signs, history of upper respiratory infection, post‐treatment complications, and IP recurrence with and without local and systemic steroid administration were studied between groups and no differences were identified. In four of six cats with bilateral disease, the second polyp was identified with advanced imaging performed at the time of referral. Conclusions and clinical importance These findings demonstrate that bilateral IP occur more frequently than reported previously and establish a prevalence for bilateral IP. These findings also highlight the value of advanced imaging techniques in diagnosing bilateral IP.

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Section: Discussionmentioning

confidence: 99%

Feline bilateral inflammatory aural polyps: a descriptive retrospective study

Hoppers

May

Frank

2020

Veterinary Dermatology

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“…7 Hearing deficits have also been reported in cats, owing to fluid in the TB or damage to the ossicles of the middle ear. 5,11…”

Section: Introductionmentioning

confidence: 99%

Retrospective study of the presentation, diagnosis and management of 16 cats with otitis media not due to nasopharyngeal polyp

Swales

Foster

Barnard³

2017

Journal of Feline Medicine and Surgery

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This small cohort shows that some cats with OM can be successfully managed medically. Surgery is invasive and may not necessarily be required if appropriate medical management is undertaken. This is the first study of OM treatment in cats and provides the basis for further studies, which should aim to establish specific infectious causes of OM and how they can potentially be managed with medical therapies.

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“…A default setting with auditory clicks (click duration of 0.1 millisecond) was used. Each recorded BAER was a mean of neural activity after 300 stimuli at 90 dB, normal hearing level 37 . For each test on each dog, a graphic representation of positive and negative peaks denoting the mean neuronal activity resulting from external acoustic stimuli was obtained.…”

Section: Methodsmentioning

confidence: 99%

“…Each recorded BAER was a mean of neural activity after 300 stimuli at 90 dB, normal hearing level. 37 For each test on each dog, a graphic representation of positive and negative peaks denoting the mean neuronal activity resulting from external acoustic stimuli was obtained. Each wave represents overall neuronal activity in one or more cortical and subcortical brain structures.…”

Section: Brainstem Auditory Evoked Response Testingmentioning

confidence: 99%

Safety and tolerability of 0.1% tacrolimus solution applied to the external ear canals of atopic beagle dogs without otitis

Kelley

Flynn-Lurie

House

et al. 2010

Veterinary Dermatology

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Tacrolimus is a nonsteroidal alternative to treat noninfectious otitis externa (OE) in people. This 21-day study investigated whether twice daily application (0.2 mL/dose) of sterile olive oil based 0.1% tacrolimus suspension in ears of atopic beagle dogs without OE was associated with adverse local reactions, development of OE, change in otic cytology, vestibular dysfunction, or hearing loss detected by brainstem auditory evoked response (BAER). The study was randomized, double-blinded, and placebo-controlled. Twenty-two dogs matched for age and sex were randomized to tacrolimus or vehicle control treatment groups. Two investigators independently evaluated dogs for signs of adverse effects including OE the first 4 days of treatment, then every 3 days. A logistic regression model was fit for each investigator's clinical scores (SAS, 9.2, 2008). Time (P = 0.0032) and group (P = 0.0167) were always significant for OE. Inter-observer reliability of clinical scores was strong, measured using Kappa coefficients and proportion of agreement. All nine exclusions (7/10 control- and 2/12 tacrolimus-treated dogs) were excluded for yeast OE. Inter-observer agreement to exclude was 100%. All dogs not excluded had normal BAER assessments before treatment, weekly during treatment, and after 21 days of treatment. None showed vestibular abnormalities at these times. Tacrolimus blood concentrations (Abbott IMx Tacrolimus II) were below detection limits (3 ng/mL) at baseline and after 21 days of treatment. Results suggest otic application of olive oil based tacrolimus suspension to canine ears with intact tympanic membranes is unlikely to result in hearing loss or vestibular dysfunction but yeast OE is a possible risk.

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Analysis of auditory and neurologic effects associated with ventral bulla osteotomy for removal of inflammatory polyps or nasopharyngeal masses in cats

Cited by 32 publications

References 29 publications

Feline bilateral inflammatory aural polyps: a descriptive retrospective study

Feline bilateral inflammatory aural polyps: a descriptive retrospective study

Retrospective study of the presentation, diagnosis and management of 16 cats with otitis media not due to nasopharyngeal polyp

Safety and tolerability of 0.1% tacrolimus solution applied to the external ear canals of atopic beagle dogs without otitis

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