Abstract:The main purpose of this paper is to develop a framework for the process design stage of production system life cycle (PSLC) using weighted interpretive structural modelling (ISM) and MICMAC analysis. In the present study, various quality enabled factors (QEFs) of process design stage has been identified through the extensive literature analysis and opinions of industrial and academic experts. In order to validate the identified QEFs, a questionnaire survey has been utilised. Then, QEFs are analysed by using ISM approach in order to develop the relationship among the considered QEFs. Afterwards, Matriced Impacts Croises Multiplication Appliqueeaun Classement (MICMAC) analysis is used to identify the driving and dependence power of QEFs. Lastly, a method of effectiveness index (EI) has been used for identifying the key areas of process design stage of PSLC. This index can be effectively utilised by the manufacturing organisations to benchmark their process design phase through effectively utilising the QEFs reported in this work.Keywords: process design; production system; quality enabled factors; QEFs; interpretive structural modelling; ISM; effectiveness index; EI; Matriced Impacts Croises Multiplication Appliqueeaun Classement; MICMAC.Reference to this paper should be made as follows: Attri, R. and and Grover, S. Developing the weighted ISM-MICMAC framework 95 journals and conferences. He guides research at post-graduate and doctorate levels, and his research areas include total quality management, manufacturing management, and human resource management. With more than 20 years of teaching and research experience, currently he is working as a Professor in the