a b s t r a c t a r t i c l e i n f o Available online xxxxThe highway geometric design guidelines for several countries provide suggestions for the coordination of horizontal curves overlapping with sag vertical curves (sag combinations) to avoid combined configurations that produce undesirable optical effects and reduced safety. Such suggestions are derived from studies based on the drawing of the perspective of the road. This drawing method is severely limited with respect to the simulation of the perspective view of the highway to the driver during the dynamic task of driving. Interactive driving simulation methods are deemed to be more efficient for these objectives. This paper reports the results of a study carried out using an interactive driving simulator to evaluate the effects on the driver's speed behavior of different configurations of sag combinations and non-combined curves on a flat grade with the same features as the horizontal curves of the sag combinations (reference curves). The speed behaviors of drivers along the tangent-curve transitions of sag combinations and reference curves were recorded. The speed on the approach tangent, the speed at the midpoint of the horizontal curve and the maximum speed reduction (MSR), the difference between the maximum speed on the last 200 m of the approach tangent and the minimum speed on the first half of the horizontal curve, were analyzed. One-way repeated MANOVA was performed to determine if the driver's speed behavior on the horizontal curves was influenced by different configurations of sag combinations and reference curves. The primary result was that on suggested sag combinations, the driver's speed behavior did not differ in any statistically significant way from that on the reference curves. Whereas the critical sag combinations (configurations that should be avoided) caused high values of maximum speed reduction along the tangent-curve transition, which pointed to the driver's reaction to an incorrect perception of the road alignment. Therefore, this result confirmed the effectiveness of the road design guidelines for the coordination of horizontal curves and sag vertical curves.