Analysis of Carbendazim in Agricultural Samples by Laser Desorption and REMPI Time-of-Flight Mass Spectrometry

Orea, J.M.; Bescós, B.; Montero, and C.; Ureña, A. Gonzalez

doi:10.1021/ac970443u

Cited by 19 publications

(15 citation statements)

References 36 publications

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“…To perform the resonance enhanced mass spectrometric analysis it is necessary to know the highly resolved REMPI spectrum of the compound to be analysed so as to find the optimal wavelength for selective ionisation. As described in a previous paper [49] our group has found the REMPI spectrum of carbendazim lying between 280 and 283 nm, with a significant maximum at 281.1 nm, as it is displayed in Figure 3. Pressure in the Ionization Chamber (mbar)…”

Section: Resultssupporting

confidence: 73%

Study of Agricultural Samples by Laser Desorption Coupled With Resonance‐Enhanced MultiphotonIonization and Time‐of‐Flight Mass Spectrometry: Application to Carbendazim Analysis in Pepper

et al. 1998

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A method for the analysis of carbendazim in peper has been developed using Supercritical Fluid Extraction (SFE) for the sample preparation and the combination of Laser Desorption (LD) with Resonance Enhanced Multi-Photon Ionization (REMPI) coupled to Time-of-Flight Mass Spectrometry (TOF-MS) for the detection. The method allows the analysis of carbendazim in pepper reducing the sample preparation step and avoiding the matrix effects present in classical GC and HPLC techniques, as well as the problems related to the labile properties of carbendazim. The detection limit obtained is of the same order of magnitude as the generally employed HPLC technique, but with higher sensitivity and easier sample preparation.

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Section: Resultssupporting

confidence: 73%

Study of Agricultural Samples by Laser Desorption Coupled With Resonance‐Enhanced MultiphotonIonization and Time‐of‐Flight Mass Spectrometry: Application to Carbendazim Analysis in Pepper

et al. 1998

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“…The experimental set-up has been already described elsewhere [23], so only a brief description is given here. Essentially, it consists of two independent high vacuum chambers; the first chamber is used for both laser desorption and laser post-ionisation of the sample followed by the ions acceleration towards the second chamber, basically a linear time-offlight unit with a dual microchannel plate detector.…”

Section: Methodsmentioning

confidence: 99%

Non-volatile analysis in fruits by laser resonant ionization spectrometry: application to resveratrol (3,5,4′-trihydroxystilbene) in grapes

Montero

Orea

Muñoz

et al. 2000

Applied Physics B: Lasers and Optics

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Abstract.A laser desorption (LD) coupled with resonanceenhanced multiphoton ionisation (REMPI) and time-of-flight mass spectrometry (TOFMS) technique for non-volatile trace analysis compounds is presented. Essential features are: (a) an enhanced desorption yield due to the mixing of metal powder with the analyte in the sample preparation, (b) a high resolution, great sensitivity and low detection limit due to laser resonant ionisation and mass spectrometry detection. Application to resveratrol content in grapes demonstrated the capability of the analytical method with a sensitivity of 0.2 pg per single laser shot and a detection limit of 5 ppb. 42.62.Fi; 82.80.Ms One of the crucial problems in the development of new analytical methods, specially in the case of food samples, is the detection and identification of non-volatile organic compounds present at low concentration levels. Although mass spectrometry nowadays is widely used in the analysis of such compounds providing exact mass identification, the difficulty lies in their volatilisation into the gas phase prior to injection into the analyser. This first-step requirement is particularly a problem for thermally labile samples as they rapidly decompose upon heating. PACS:To circumvent this difficulty a wide range of techniques have been developed for non-volatile analysis. Namely:, plasma desorption mass spectrometry (PDMS) [4] and secondary ion mass spectrometry (SIMS) [5]. In spite of the significant improvement and extended applicability of these methods they all suffer of the same limitation derived from the fact that both desorption and ionisation cannot be separately optimised, which, obviously, may be critical for many real applications. matrix-assisted laser desorption/ionisation (MALDI) technique is widely used for ion generation in many mass spectrometric analytical applications [6]. This is accomplished by mixing the analyte with an excess of cromophore matrix so as to improve both the desorption and ionisation processes, especially in the case of protein and polymer analysis. However, due to the complexity of the process, finding the best cromophore or matrix for a particular analyte is not always straightforward. A significant improvement using the MALDI technique was obtained by the so-called ultra fine metal plus liquid matrix method (UFP) for sample preparation [7]. This procedure increases the yield of high-mass ions and prolongs their production time.More recently, laser desorption methods have been developed in which volatilisation and ionisation steps are separated and so higher sample sensitivity is achieved. While all them have in common the laser desorption step they differ in their ionisation method. Within this category the laser multiphoton ionisation coupled with time-of-flight mass spectrometry, and in particular resonance-enhanced multiphoton ionisation (REMPI)-time-of-flight mass spectrometry (TOFMS) can be considered as one of the most powerful methods for the analysis of trace components in complex matrix [8][9][10][11][12][1...

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“…Work is in progress along this direction for analysis of solid materials, and specifically for agricultural samples. First results from this research activity has been the subject of a recent publication [33].…”

Section: Discussionmentioning

confidence: 99%

Laser Desorption Dynamics of Carbendazim on a Glass Surface

2000

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A study on the desorption of carbendazim (methyl-2-benzimidazolecarbamate, mass = 191 amu) from a glass surface (Pyrex) has been carried out using an experimental set-up based on laser desorption and laser post-ionization followed by time-of-flight mass spectrometry. After optimization of the experimental conditions a resolution of ca. 850 was achieved at the mass of the pesticide (191 amu). All measured time-of-flight mass spectra showed not only an excellent signal to noise ratio, but also the lack of significant molecular fragmentation, except for a mass of 71 amu which was attributed to the lateral chain of the carbendazim. Neutral time-of-flight yields were measured for several desorption energies. Analysis of the corresponding velocity distributions suggests a thermal mechanism dominating the laser-induced desorption. Finally the capability of the present technique for analytical applications is also discussed.

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Analysis of Carbendazim in Agricultural Samples by Laser Desorption and REMPI Time-of-Flight Mass Spectrometry

Cited by 19 publications

References 36 publications

Study of Agricultural Samples by Laser Desorption Coupled With Resonance‐Enhanced MultiphotonIonization and Time‐of‐Flight Mass Spectrometry: Application to Carbendazim Analysis in Pepper

Study of Agricultural Samples by Laser Desorption Coupled With Resonance‐Enhanced MultiphotonIonization and Time‐of‐Flight Mass Spectrometry: Application to Carbendazim Analysis in Pepper

Non-volatile analysis in fruits by laser resonant ionization spectrometry: application to resveratrol (3,5,4′-trihydroxystilbene) in grapes

Laser Desorption Dynamics of Carbendazim on a Glass Surface

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