Analysis of clinical characteristics of mirror and TV signs in Alzheimer's disease and dementia with Lewy bodies

Abstract

Objective This study explored the clinical features of dementia with Lewy bodies (DLB) and Alzheimer's disease (AD) and analyzed the differences in neurologic syndromes, including mirror and TV signs, between different groups. Methods Patients with AD and DLB (325 and 115, respectively) hospitalized in our institution were enrolled. We compared psychiatric symptoms and neurologic syndromes between the DLB and AD groups and within each subgroup, including the mild-moderate and severe subgroups. Results The prevalence rates of visual hallucination, parkinsonism, rapid eye movement sleep behavior disorder, depression, delusion, and the Pisa sign were significantly higher in the DLB group than in the AD group. Furthermore, within the mild-moderate subgroup, the mirror sign and Pisa sign prevalence rates were significantly higher in the DLB group than in the AD group. In the severe subgroup, no significant difference was found in any neurologic sign between the DLB and AD groups. Conclusion Mirror and TV signs are rare and often disregarded because they are not usually invoked during routine inpatient or outpatient interviews. According to our findings, the mirror sign is uncommon in early AD patients but common in early DLB patients and should receive increased attention.

Importance of Capgras syndrome in shared psychotic disorder: a case report

“…The syndrome occurs in a variety of psychiatric and organic disorders but appears to be strongly associated with schizophrenia. 5,6 The most common type of delusional misidentification syndrome is Capgras syndrome, which is manifested by delusional denial of identification of familial people and the belief that they have been replaced by strangers who are physically but not psychologically identical to the misidentified person. Patients with this syndrome believe that an identical stranger has replaced someone significant to them.…”

“…The syndrome occurs in a variety of psychiatric and organic disorders but appears to be strongly associated with schizophrenia. 5 , 6 …”