2020
DOI: 10.1371/journal.pone.0235459
|View full text |Cite
|
Sign up to set email alerts
|

Analysis of clinical features and early warning signs in patients with severe COVID-19: A retrospective cohort study

Abstract: Coronavirus disease 2019 (COVID-19) was first identified in Wuhan, China, in December 2019. Although previous studies have described the clinical aspects of COVID-19, few studies have focused on the early detection of severe COVID-19. Therefore, this study aimed to identify the predictors of severe COVID-19 and to compare clinical features between patients with severe COVID-19 and those with less severe COVID-19. Patients admitted to designated hospital in the Henan Province of China who were either discharged… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
1

Citation Types

1
11
0
1

Year Published

2020
2020
2023
2023

Publication Types

Select...
6
1

Relationship

0
7

Authors

Journals

citations
Cited by 15 publications
(14 citation statements)
references
References 20 publications
1
11
0
1
Order By: Relevance
“…Liu et al . [ 21 ], in a research to determine the risk factors for severe COVID-19, report that fever, cough and fatigue appear as the main symptoms among the participants, with fever being the most common initial symptom (92.3%). Rivera-Izquierdo et al .…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…Liu et al . [ 21 ], in a research to determine the risk factors for severe COVID-19, report that fever, cough and fatigue appear as the main symptoms among the participants, with fever being the most common initial symptom (92.3%). Rivera-Izquierdo et al .…”
Section: Discussionmentioning
confidence: 99%
“…It is noteworthy that the fever symptom appears as an important indicator in the screening of suspected or confirmed cases of COVID-19, despite not having, in this study, a strong relationship with the length of hospital stay. Liu et al [21], in a research to determine the risk factors for severe COVID-19, report that fever, cough and fatigue appear as the main symptoms among the participants, with fever being the most common initial symptom (92.3%). Rivera-Izquierdo et al [22] complement that in patients admitted for COVID-19 at Hospital Universitario Clínico San Cecilio, Spain, the most frequent clinical picture was also due to low fever (89.5%) and dry cough (80.7%), followed by general malaise (63.5%), dyspnea (61.3%) and tiredness (59.2%).…”
Section: Plos Onementioning
confidence: 99%
“…In addition, a large number of studies, albeit with small sample sizes, have examined the association between individual co‐morbidities, 20‐23 or laboratory and/or imaging abnormalities 8,24,25 . Several reports have reported predictors of disease severity, unfortunately with widely differing definitions of severe illness 26‐28 . We could find only one larger cohort of hospitalized patients with COVID‐19 from the US reporting independent predictors of mortality among 1304 hospitalized patients with COVID‐19 18 .…”
Section: Discussionmentioning
confidence: 90%
“…8,24,25 Several reports have reported predictors of disease severity, unfortunately with widely differing definitions of severe illness. [26][27][28] We could find only one Abbreviations: ANC, absolute neutrophil count; ARDS, acute respiratory distress syndrome; BMI, body mass index; CVD, cerebrovascular disease; CHD, coronary heart disease; COVID-19, coronavirus disease 2019; CRP, C-reactive protein; CT, computed tomography; DM, diabetes mellitus; HR, hazard ratio; LDH, lactate dehydrogenase; NSAID, nonsteroidal anti-inflammatory drugs; OR, odds ratio; SOFA, sequential organ failure assessment; Tn, troponin; ULN, upper limits of normal; WCC, white cell count.…”
Section: Discussionmentioning
confidence: 99%
“…Além disso, acredita-se que o vírus possa danificar os linfócitos, prejudicando o sistema imunológico durante o curso da doença. Por fim, concentrações elevadas de PCR estão correlacionadas com um maior risco de falência e morte de órgãos(LIU et al, 2020).…”
unclassified