Analysis of Colonoscopic Findings in the Differential Diagnosis Between Intestinal Tuberculosis and Crohn’s Disease

Abstract

A systematic analysis of colonoscopic findings is very useful in the differential diagnosis between intestinal tuberculosis and Crohn's disease.

Ileoscopy in patients with ileocolonic tuberculosis

“…In most other studies, nonspecific inflammatory changes on histology coupled with a good response to antituberculous a g e n t s has been taken to be evidence of colonic tuberculosis [1][2][3][4][5]7,39,40] . We deliberately did not include these cases, as that would have led to some speculation about the diagnosis.…”

“…We deliberately did not include these cases, as that would have led to some speculation about the diagnosis. In such cases a close monitoring of the patients is of utmost importance and the approach may be clinically very relevant if on a close follow-up these patients show a good response to the drugs [1][2][3][4][5]7,[39][40] . The poor sensitivity of the colonic biopsies is due the fact that most lesions are located in the submucosa and are not sampled by the biopsy.…”

Inflammatory Bowel Disease in Korea: Epidemiological, Genomic, Clinical, and Therapeutic Characteristics

“…Using these endoscopic parameters, the diagnosis of either intestinal tuberculosis or CD was correctly made in 87.5% of patients. 18 In Asia, if a patient has an ulceration in the ileocecal region, intestinal Behçet's disease (BD) should be included as a differential diagnosis. 35 In an effort to differentiate intestinal BD and CD, a Korean study reported that round ulcerations, ≤5 in number, focal distributions, and absence of aphthous and cobblestone lesions were dominant features in intestinal BD.…”

“…1,9 This review will describe the updated data on Korean IBD patients based on the recent publications. 1,8,[11][12][13][14][15][16][17][18][19][20] …”

Clinical Aspects of Idiopathic Inflammatory Bowel Disease: A Review for Pathologists

“…In this study, anorectal lesions, longitudinal ulcers, aphthous ulcers, and a cobblestone appearance were significantly more common in CD, whereas involvement of fewer than 4 segments, a patulous ileocecal valve, transverse ulcers, and scars or pseudopolyps were common in ITB. 153 Recent studies incorporated the findings of computed tomography enterography such as intestinal fistulas, target signs, comb signs-a prominence of vasa recta in the mesentery-and lymph node enhancement, and showed an improved diagnostic accuracy. which ileocecal involvement is the most common.…”