Analysis of Complications and Recipients' and Graft Survival in Patients 60 Years of Age and Older in the Long-Term Follow-up Period After Kidney Transplant: A Single-Center, Paired Kidney Analysis

Skrabaka, Damian; Kolonko, Aureliusz; Sekta, Sylwia; Czerwiński, Jarosław; Owczarek, Aleksander; Valenta, Zdeněk; Król, Robert; Wiȩcek, Andrzej; Ziaja, Jacek

doi:10.1016/j.transproceed.2022.03.038

Cited by 3 publications

(2 citation statements)

References 23 publications

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“…Creatinine at 5-year follow-up was higher in the age ≥60 group, and patient mortality was higher in this group (15.4% vs 8.0%; P < .05). 23 The increased mortality in the older group is not unexpected due to the lower life expectancy and increased incidence of comorbidities at baseline in this group.…”

Section: Kidney Transplantationmentioning

confidence: 84%

“…Skrabaka et al analyzed the effect of recipient age on both short- and long-term outcomes in a prospective trial of 350 patients. 23 In a paired analysis, 175 patients age ≥60 years old were matched with 175 patients age <60 years old to receive kidneys from the same donor in order to reduce the influence of donor factors on outcomes. The ≥60-year-old group had an increased incidence of diabetes and cardiovascular disease at baseline.…”

Section: Kidney Transplantationmentioning

confidence: 99%

See 1 more Smart Citation

Abdominal Organ Transplantation: Noteworthy Literature in 2022

Nolasco

Igwe

Sakai

2023

Semin Cardiothorac Vasc Anesth

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This review highlights noteworthy literature published in 2022 pertinent to anesthesiologists and critical care physicians caring for patients undergoing abdominal organ transplantation. We begin by exploring the impacts that the COVID-19 pandemic has had across the field of abdominal organ transplantation, including the successful use of grafts procured from COVID-19-infected donors. In pancreatic transplantation, we highlight several studies on dexmedetomidine and ischemia-reperfusion injury, equity in transplantation, and medical management, as well as studies comparing pancreatic transplantation to islet cell transplantation. In our section on intestinal transplantation, we explore donor selection. Kidney transplantation topics include cardiovascular risk management, obesity, and intraoperative management, including fluid resuscitation, dexmedetomidine, and sugammadex. The liver transplantation section focuses on clinical trials, systematic reviews, and meta-analyses published in 2022 and covers a wide range of topics, including machine perfusion, cardiovascular issues, renal issues, and coagulation/transfusion.

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Section: Kidney Transplantationmentioning

confidence: 84%

Section: Kidney Transplantationmentioning

confidence: 99%

Abdominal Organ Transplantation: Noteworthy Literature in 2022

Nolasco

Igwe

Sakai

2023

Semin Cardiothorac Vasc Anesth

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The comprehensive incidence and risk factors of fracture in kidney transplant recipients: A meta‐analysis

Jia,

Chao,

Yang

et al. 2024

Nephrology

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AimKidney transplant recipients are at high risk of fracture due to many factors such as nutritional status, hyperparathyroidism, acidosis and steroid administration. The current meta‐analysis aimed to comprehensively analyse the incidence and risk factors of fracture in kidney transplant recipients.MethodsA systematic search on Embase, Web of Science, PubMed and Cochrane Library until November 2023 was performed. RStudio software was used to analyse data.ResultsTwenty‐eight eligible studies containing 310 530 kidney transplant recipients were included in the analysis. The pooled incidence of fracture was 10% (95% confidence interval [CI]: 7%–13%) generally. When divided by regions, it was further observed that the pooled incidence of fracture was 13% (95% CI: 9%–17%) in Europe, 11% (95% CI: 6%–16%) in North America, 7% (95% CI: 3%–11%) in Asia. Regarding the risk factors, pooled analysis revealed that age of recipient (hazard ratio [HR] = 1.50, 95% CI: 1.17–1.91), female sex (HR = 1.45, 95% CI: 1.36–1.53), pretransplantation diabetes (HR = 1.76, 95% CI: 1.58–1.97), pretransplantation fracture history (HR = 2.28, 95% CI: 1.86–2.78), dialysis duration (HR = 1.09, 95% CI: 1.01–1.17) and deceased donor (HR = 1.21, 95% CI: 1.05–1.39) related to higher risk of fracture. The general quality of included studies was acceptable, and no publication bias existed except for the analysis between age of recipient and fracture incidence; further trim and fill method indicated age of recipient showed a correlation trend with the fracture incidence without the statistical significance.ConclusionThe pooled incidence of fracture reaches 10% in kidney transplant recipients, which relates to age of recipient, female sex, pretransplantation diabetes or fracture history, dialysis duration and decease donor.image

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Urinary stasis in a transplanted kidney: 20 years of experience of one transplant center

et al. 2023

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Introduction. Urinary stasis in transplanted kidney occurs due to ureteral obstruction caused by intrinsic or extrinsic etiological factors. The aim of this study was to determine the prevalence, time of occurrence and etiopathogenetic factors of urinary stasis and their distribution according to the type of kidney donor. And to analyze the success of different types of surgical and conservative treatment. Methods. The retrospective-prospective randomized study included 580 patients transplanted in Transplant Center, Clinic of Urology, Clinical Center of Serbia for a period of 20 years. After diagnosing urinary stasis, minimally invasive or open surgical interventions were performed, while for one group of patients the definitive treatment was non-surgical with observation and active monitoring. The main control parameters during non-surgical treatment were diameter of pyelon, serum creatinine values and urine culture findings. Results. Urinary stasis was found in 15% of transplanted patients. The largest number of transplanted patients had early urinary stasis, within 3 months of transplantation (68%). The most common etiological factors of urinary stasis were intrinsic factors (66%), which were significantly more frequent in transplant patients from a living donor. Non-surgical treatment with observation and active monitoring was successfully performed in 22% of patients. Conclusion. The largest number of transplanted patients with urinary stasis has been successfully treated surgically, most often with open surgery. Surgical correction is advised in cases of pronounced dilatation of the canalicular system with a tendency to increase, in progressive decrease in renal function and recurrent complicated urinary infections refractory to antibiotic therapy.

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Analysis of Complications and Recipients' and Graft Survival in Patients 60 Years of Age and Older in the Long-Term Follow-up Period After Kidney Transplant: A Single-Center, Paired Kidney Analysis

Cited by 3 publications

References 23 publications

Abdominal Organ Transplantation: Noteworthy Literature in 2022

Abdominal Organ Transplantation: Noteworthy Literature in 2022

The comprehensive incidence and risk factors of fracture in kidney transplant recipients: A meta‐analysis

Urinary stasis in a transplanted kidney: 20 years of experience of one transplant center

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