Analysis of Complications of Acute Coronary Syndrome and Their Outcomes in India

Abstract

This study was conducted to reflect the clinical profile of patients presented to Emergency department (ED) with complications of acute coronary syndrome in developing country like India. This prospective cohort study was conducted in a cohort of 50 patients' with acute coronary syndrome (ACS). They were followed up an over duration of three months for the outcome during hospitalization. Male; smoker; age > 60 years; hypertension were representative risk factors for this cohort. More than 96% of patients presented with chest pain, mostly in early morning hours. Thrombolysis was given to 46 patients (92%); and out of these, 21 (42%) patients succumbed to death. This study emphasised mainly on health education on adoption of health lifestyles and symptoms; early access to health care algorithm control of hypertension and related morbidities. The study has also tried to address need of policy ramification for strengthening for Non-communicable diseases in developing countries. ReseaRch study-PRosPective cohoRt Check for updates Methodology This prospective cohort study was conducted over duration of three months in one of the government medical college in India. Government medical college in India provide free medical care. Medical college

Ticagrelor Versus Clopidogrel in ST Segment Elevation Myocardial Infarction Patients Candidate for Primary Percutaneous Coronary Intervention

“…Acute coronary syndrome (ACS) is a major cause of death and disability-adjusted life years lost worldwide. 1,2 Clinically, ACS presents with acute persistent chest pain or other symptoms suggestive of cardiac ischemia and either ST segment elevation in at least 2 adjacent leads with abnormal cardiac biomarkers (ST elevation myocardial infarction or STEMI), ST segment depression, and/or T wave inversion with abnormal cardiac biomarkers (non-ST elevation myocardial infarction or NSTEMI), or ECG changes indicative of ischemia without abnormal cardiac biomarkers (unstable angina). [3][4][5] As per the current American College of Cardiology/American Heart Association guidelines, STEMI and NSTEMI patients are recommended to receive dual antiplatelet therapy (aspirin and P2Y12 platelet inhibitor).…”

Cardiovascular Outcomes in Acute Coronary Syndrome and Malnutrition

“…Mortality following acute coronary syndrome (ACS) remains high, and life-threatening coronary artery disease is often predisposed by cardiovascular disease (CVD) risk factors such as type 2 diabetes mellitus, hypertension, and dyslipidemia. 1 Emerging evidence has shown a possible J-curve association between nutrition and CVD, and the identification of this modifiable risk factor may potentially allow for better risk stratification of patients with ACS. 1 , 2 Various nutritional assessment tools used to categorize malnutrition, such as the Prognostic Nutrition Index (PNI), Geriatric Nutritional Risk Index (GNRI), and Controlling Nutritional Status (CONUT), have been developed and demonstrated to possess prognostic utility in the prognostication of ACS.…”

“… 1 Emerging evidence has shown a possible J-curve association between nutrition and CVD, and the identification of this modifiable risk factor may potentially allow for better risk stratification of patients with ACS. 1 , 2 Various nutritional assessment tools used to categorize malnutrition, such as the Prognostic Nutrition Index (PNI), Geriatric Nutritional Risk Index (GNRI), and Controlling Nutritional Status (CONUT), have been developed and demonstrated to possess prognostic utility in the prognostication of ACS. 3 , 4 , 5 These past studies have postulated that hypoalbuminemia is correlated with a proinflammatory environment, although the exact cause-and-effect mechanism between them is unclear.…”