Analysis of CT and MRI Combined Examination for the Diagnosis of Acute Cerebral Infarction

Zhang, Wenbo; Cheng, Jingliang; Zhang, Yong; Wang, Keyan; Jin, Hongrui

doi:10.29271/jcpsp.2019.09.898

Cited by 25 publications

(16 citation statements)

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“… 2 Compared with conventional CT, spiral CT can perform volume scanning in a short period of time, reduce the artifacts caused by motion of patients, and significantly improve the spatial resolution and density resolution, so that early detection of diseased patients. 3 , 4 This review intends to briefly introduce the CT imaging features of cerebral infarction, to explore the effectiveness of the CT examination in promoting the physical function restoration.…”

Section: Introductionmentioning

confidence: 99%

Application of Quantitative CT Imaging in Rehabilitation Nursing of Cerebral Apoplexy Patients

2021

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Objectives: Electronic computed tomography (CT) is an important imaging method for the diagnosis of cerebral infarction. This paper explores the preventive effects of quantitative CT imaging and early rehabilitation nursing on patients with cerebral apoplexy and shoulder-hand syndrome. Methods: Sixty cerebral apoplexy patients treated were included as control group and given routine care from September 2018 to May 2020. Sixty cerebral apoplexy patients were included as observation group, and early rehabilitation nursing intervention was given based on control group. The incidence of shoulder-hand syndrome and upper limb function were compared between the two groups, to explore the effectiveness of the CT examination in promoting the physical function restoration. Results: The incidence of shoulder-hand syndrome in observation group after three months of intervention was lower than that in control group, and the severity was less than that in control group (P<0.05); The Ashworth score of muscle tension in observation group after three months of intervention was lower than that in control group, and the simplified FMA score of the upper limbs was higher than that in control group. Conclusion: Early rehabilitation nursing intervention after CT examination can prevent the occurrence of cerebral apoplexy and shoulder-hand syndrome and improve upper limb function, which is worthy of promotion. doi: https://doi.org/10.12669/pjms.37.6-WIT.4840 How to cite this:Yan B, Zhang H, Liu J. Application of Quantitative CT Imaging in Rehabilitation Nursing of Cerebral Apoplexy Patients. Pak J Med Sci. 2021;37(6):1574-1579. doi: https://doi.org/10.12669/pjms.37.6-WIT.4840 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Section: Introductionmentioning

confidence: 99%

Application of Quantitative CT Imaging in Rehabilitation Nursing of Cerebral Apoplexy Patients

2021

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“…There have been studies on the diagnostic value of C‐reactive protein and interleukin‐6 in ACI, but their specificity is not high 3–5 . At present, the diagnosis of ACI depends on the Stroke Scale score, computed tomography (CT), magnetic resonance imaging (MRI) and other imaging methods 6 . Imaging examination is of great significance to exclude hemorrhagic stroke, but CT examination cannot show the ischemic focus well in the early stage of infarction, while MRI examination is not applicable for some patients with metal stents 4,6 .…”

Section: Introductionmentioning

confidence: 99%

“…At present, the diagnosis of ACI depends on the Stroke Scale score, computed tomography (CT), magnetic resonance imaging (MRI) and other imaging methods 6 . Imaging examination is of great significance to exclude hemorrhagic stroke, but CT examination cannot show the ischemic focus well in the early stage of infarction, while MRI examination is not applicable for some patients with metal stents 4,6 . Therefore, it is important to find sensitive biomarkers for accurate diagnosis and prognosis evaluation of ACI.…”

Section: Introductionmentioning

confidence: 99%

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Plasma miR‐409‐3p promotes acute cerebral infarction via suppressing CTRP3

Song

Zhu

2020

The Kaohsiung J of Med Scie

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Abnormal expression of miR-409-3p has been found in several neurodevelopmental disorders, but whether it is dysregulated in the patients with acute cerebral infarction (ACI) has not been evaluated. The current study mainly focused on the clinical significance and the underlying mechanism of plasma miR-409-3p in the progression of ACI. The level of plasma miR-409-3p was determined in ACI patients (n = 80) and healthy controls (n = 30). Pearson correlation assay was performed to evaluate the association and cardiovascular risk factors. A receiver operating characteristic curve (ROC) was used to evaluate the diagnostic value of plasma miR-409-3p levels in patients with ACI. Dual luciferase reporter assay and western blot were performed to determine the possible target gene of miR-409-3p. Our data showed that the expression of plasma miR-409-3p in the ACI group was higher than that in the healthy controls. Furthermore, Pearson correlation analysis indicated a positive correlation between plasma miR-409-3p and the NIHSS score. ROC analysis indicated that plasma miR-409-3p could differentiate plasma miR-409-3p in ACI patients from healthy controls. Then, we explored the possible target genes of miR-409-3p. Interestingly, C1q and TNF-related 3 (CTRP3), a novel adipose tissue-derived secreted factor, was found to be a target gene of miR-409-3p. We found that knockdown of CTRP3 significantly induced PC12 cell apoptosis, even in PC12 cells transfected with miR-409-3p inhibitor. These data suggested that miR-409-3p induced PC12 cell apoptosis by targeting CTRP3. Altogether, elevated plasma miR-409-3p is correlated with disease severity and may be efficient for the early diagnosis of ACI.

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“…[5,6] Так, W. Zhang і співавт. [7] довели, що застосування КТ в поєднанні з магнітно-резонансною томографією для підтвердження діагнозу інфаркту головного мозку дає кращі результати, ніж показник проведеного тільки КТ-дослідження (р<0,001).…”

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Time since hemorrhages of traumatic and non-traumatic genesis into the substance of the human brain formation using distribution of linear dichroism fluctuations reconstruction

Garazdiuk¹

2021

СМЕ

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For a forensic expert-practitioner, it is especially important to objectively diagnose and time since the formation of hemorrhage (TSFH) in the substance of the human brain (SHB) of traumatic and non-traumatic origin, as there are cases when the external examination of the corpse at the scene are absent, and at internal research find hemorrhages in a brain. In forensic practice, to verify the cause of death, physical-optical methods are successfully used, which are based on laser irradiation of biological tissues with subsequent mathematical and statistical processing of the obtained data. Previous studies on the possibility of differentiating the cause of death by traditional polarization methods have yielded positive results, which suggests the possibility of their suitability for verification of the genesis of hemorrhage into the brain. For a forensic expert-practitioner, the main thing is objectivity, accuracy and speed of obtaining the result, which could fully satisfy the methods of laser polarimetry in the case of determining the TSFH of traumatic and non-traumatic origin in SHB. Therefore, it is necessary to continue the development and research of these methods for this purpose. Aim of the work. To substantiate the possibility of using the method of differential Mueller-matrix mapping of phase anisotropy to determine the temporal dynamics of maps of linear birefringence of histological sections of human brain in determining the age of hemorrhage in human brain substance and to develop forensic criteria for determining the age. death due to cerebral infarction of ischemic and hemorrhagic origin. Materials and methods. To achieve this goal, we studied native histological preparations SHB from 130 corpses with a known time of death. The cause of death was TBI (group II (n=35)), cerebral infarction of ischemic origin (group III (n=32)), hemorrhagic stroke (group IV (n=33)), acute coronary insufficiency (group I – comparison group (n=30)). The values of the distribution of the coordinates of the polarization parameters at the points of the microscopic images at the location of the standard Stokes polarimeter were measured. Experimental measurements of Stokes-parametric images of biological layers were performed according to the method presented in the sources. Subsequently, the obtained data were subjected to statistical processing and evaluation of the obtained results. Statistical moments (SM) of the 1st-4th orders (mean (SM1), variance (SM2), asymmetry (SM3) and excess (SM4)) of each map were determined. Results and discussion. Comparative analysis of polarization Mueller-matrix mapping images of SHB sections from all groups revealed the destruction of the polycrystalline structure formed by optically active protein complexes of the brain substance, which indicates a decrease in absolute values and range of their scatter with increasing hemorrhage time. This is indicated by the coordinate inhomogeneity of the Mueller-matrix invariant maps of histological sections of SHB of all groups. For histograms that characterize the distributions of the Mueller-matrix invariant samples from all (comparison groups 1 and experimental 2-4) groups, are characterized by individual and significant variations in the values of statistical moments. Due to this, with increasing hemorrhage time, the value of the mean (SM1) and variance (SM2) decreases. Asymmetry (SM3) and excess (SM4), on the contrary, increase. The analysis of the results of statistical processing of the topographic structure of LD tomograms of fibrillar networks of histological sections of SHB dead from all groups shows a greater temporal dynamics of necrotic destruction of nervous tissue. Accordingly, there is a faster time decrease in the absolute values and the range of scatter of the LD value with increasing TSFH. That is, the diagnostic sensitivity of the statistical moments of the 3rd and 4th orders for azimuthal-invariant Mueller-matrix differentiation of nerve tissue samples of the brain of the deceased of control group 1 and all experimental groups 2-4 (p<0,05) was revealed. Conclusions. A series of studies of the effectiveness of a new in forensic practice method of differential Mueller-matrix mapping of partially depolarizing histological sections of SHB and tomographic reproduction of optical anisotropy parameters of their polycrystalline structure revealed a high level of accuracy of differentiation and formation of genesis, even under conditions of small geometric thickness of experimental samples. The range of linear change of values of statistical moments of the 1st - 4th orders which characterize distributions of size of LD of fibrillar networks of histologic sections of SHB of the dead from all groups, makes 24 h. In the range of 6-24 hours, the accuracy of determining the TSFH using statistical processing of the topographic structure of LD tomograms of fibrillar networks of histological sections of TSFH is (30±5) minutes.

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Analysis of CT and MRI Combined Examination for the Diagnosis of Acute Cerebral Infarction

Cited by 25 publications

References 3 publications

Application of Quantitative CT Imaging in Rehabilitation Nursing of Cerebral Apoplexy Patients

Application of Quantitative CT Imaging in Rehabilitation Nursing of Cerebral Apoplexy Patients

Plasma miR‐409‐3p promotes acute cerebral infarction via suppressing CTRP3

Time since hemorrhages of traumatic and non-traumatic genesis into the substance of the human brain formation using distribution of linear dichroism fluctuations reconstruction

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