Analysis of donor deferral at three blood centers in Brazil

Gonçalez, Thelma T.; Sabino, Éster Cerdeira; Schlumpf, Karen S.; Wright, David J.; Mendrone, Alfredo; Lopes, Maria Inês; Leão, Silvana Carneiro; Miranda, Carolina; Capuani, Ligia; Carneiro-Proietti, Anna Bárbara F.; Basques, Fernando Valadares; Ferreira, João Eduardo; Busch, Michael P.; Custer, Brian

doi:10.1111/j.1537-2995.2012.03820.x

Cited by 40 publications

(67 citation statements)

References 28 publications

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“…The majority of donors with low Hb were females, and this is in line with other reports worldwide 3,17, 22–24. Low Hb has been reported as a major cause of deferral in many studies reported from Turkey, Brazil, Saudi Arabia, Japan, India, and Pakistan; the results of our study is also in line with these reports 6,7,14,19,25. We believe that combining anemia prevention measures and treatment in donor recruitment strategies could help regain the donors and developing a healthy blood donor pool.…”

Section: Discussionsupporting

confidence: 93%

“…In spite of the importance of blood donor selection for blood safety, we need to consider that selection processes might have negative impacts on the blood supply, as many deferred donors might not return to donate again due to negative feelings resulting from their deferral 3,4. Hence, it is crucial to define a rational, evidence-based donor selection process and eliminate practices that lead to the unnecessary deferral of volunteered donors 5,6…”

Section: Introductionmentioning

confidence: 99%

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Analysis of blood donor pre-donation deferral in Dubai: characteristics and reasons

Shaer¹,

Sharma²,

Abdulrahman³

2017

JBM

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BackgroundTo ensure an adequate and safe blood supply, it is crucial to select suitable donors according to stringent eligibility criteria. Understanding the reasons for donor deferral can help in planning more efficient recruitment strategies and evaluating donor selection criteria. This study aims to define donor pre-donation deferral rates, causes of deferral, and characteristics of deferred donors in Dubai.Materials and methodsThis retrospective study was conducted on all donors who presented for allogeneic blood donation between January 1, 2010, until June 30, 2013, in Dubai Blood Donation Centre, accredited by the American Association of Blood Banks. The donation and deferral data were analyzed to determine the demographic characteristics of accepted and deferred donors, and frequency analyses were also conducted.ResultsAmong 142,431 individuals presenting during the study period, 114,827 (80.6%) were accepted for donation, and 27,604 (19.4%) were deferred. The overall proportion of deferrals was higher among individuals less than 21 years old (35%, P<0.000), females (44% were deferred compared to 15% of males, P<0.0001), and first-time donors (22% were deferred vs 14% of repeat donors, P<0.0001). The main causes for a temporary deferral were low hemoglobin and high blood pressure.DiscussionThe deferral rate among blood donors in Dubai is relatively high compared to the internationally reported rates. This rate was higher among first-time donors and females, with low hemoglobin as the major factor leading to a temporary deferral of donors. Strategies to mitigate deferral and improve blood donor retention are urged in Dubai to avoid additional stress on the blood supply.

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Section: Discussionsupporting

confidence: 93%

Section: Introductionmentioning

confidence: 99%

Analysis of blood donor pre-donation deferral in Dubai: characteristics and reasons

Shaer¹,

Sharma²,

Abdulrahman³

2017

JBM

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“…First-time donors were more frequently deferred than repeat donors, especially because of interview decisions and medication; this corroborates previous studies [8,22]. Although young first-time donors have the potential to increase the donor pool, temporary deferral may discourage them from returning for subsequent donation.…”

Section: Discussionsupporting

confidence: 76%

“…Recruitment, selection, and retention of voluntary non-remunerated donors from low-risk populations are the cornerstones of a safe, sustainable, and adequate national blood supply [7]. Screening, however, can lead to either temporary or permanent deferral, resulting in lower donation rates that could further limit the donor pool [8]. Early reports have shown that prospective donors who were temporarily deferred returned less frequently for subsequent donation than those who donated successfully, and this was especially true for first-time donors [9,10,11].…”

Section: Introductionmentioning

confidence: 99%

Blood Donor Deferral among Students in Northern Japan: Challenges Ahead

Ngoma¹,

Goto²,

Nollet

et al. 2014

Transfus Med Hemother

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Background: As Japan's aging society needs more blood, young students comprise a progressively smaller portion of the donor pool. To ensure a safe and sustainable blood supply, it is crucial to select suitable donors. This study aims to evaluate donor deferral rates, causes of deferral, and characteristics of deferred Japanese students. Methods: Computerized records of blood centers in northern Japan (Miyagi and Fukushima Prefectures) from March 2010 through March 2011 were retrospectively analyzed. Results: Among 231,361 individuals visiting during the 12-month period, 24,778 were students. Of these, 19,193 (77%) attempted donation, and 5,585 (23%) were deferred. Low hemoglobin, questionnaire-based interview decisions, and medication were the main reasons for temporary deferral. Age, sex, and blood center location were associated with low hemoglobin; donation history and blood center location were associated with medication-based deferral. The odds ratio among female students deferred for low hemoglobin was 35.48 with a 95% CI of 27.74-45.38. Conclusions: These results suggest that continued efforts are needed to motivate deferred potential donors to return, to prevent low hemoglobin especially among females, and to review medical interview decisions, while paying close attention to regional differences.

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“…Recife showed a lower proportion of female donations, and this may be explained by the lower socioeconomic characteristics of the state and region that can affect women’s health and eligibility to donate blood. Higher rates of deferral have already been described in Recife, especially due to a low haemoglobin level [13]. In addition, Recife has not been prioritizing campaigns focusing on recruiting more female donors.…”

Section: Discussionmentioning

confidence: 99%

The impact of policies to restrict the use of plasma containing products and apheresis platelets from female donors to mitigate transfusion related acute lung injury (TRALI) in Brazil

Blatyta

Custer

Liu

et al. 2013

Transfusion and Apheresis Science

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Background and Objectives Although the incidence of TRALI is unknown in Brazil, some blood centers have adopted strategies to prevent TRALI. We evaluated the impact of three policies to mitigate TRALI on the supply of blood products: to divert the production of whole blood-derived plasma from female donors; to defer all female donors from apheresis platelet collections, and to defer only multiparous female donors from apheresis platelet collections. Materials and Methods Data from allogeneic whole blood and apheresis platelet donations from April 2008 to December 2009 were collected in three Brazilian blood centers and the impact of the aforementioned strategies was evaluated. Results Of 544,814 allogeneic blood donations, 30.8% of whole blood plasma and 24.1% of apheresis platelet donations would be reduced if only male donor plasma was issued for transfusion and all female donors were deferred from apheresis donation, respectively. If only multiparous donors were deferred from apheresis donation, there would be a 5% decrease of all apheresis platelet collections. Conclusion Restricting the use of whole blood derived plasma to male-only donors and deferring all female apheresis platelet donors would impact two out of three Brazilian blood centers. A deferral policy on multiparous apheresis platelet donors may be acceptable as a temporary measure, but may cause more stress on a system that is already working at its limit.

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Analysis of donor deferral at three blood centers in Brazil

Cited by 40 publications

References 28 publications

Analysis of blood donor pre-donation deferral in Dubai: characteristics and reasons

Analysis of blood donor pre-donation deferral in Dubai: characteristics and reasons

Blood Donor Deferral among Students in Northern Japan: Challenges Ahead

The impact of policies to restrict the use of plasma containing products and apheresis platelets from female donors to mitigate transfusion related acute lung injury (TRALI) in Brazil

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