Analysis of drug-related problems in three departments of a German University hospital

Lenssen, Rebekka; Heidenreich, Axel; Schulz, Jörg B.; Trautwein, Christian; Fitzner, Christina; Jaehde, Ulrich; Eisert, Albrecht

doi:10.1007/s11096-015-0213-1

Cited by 60 publications

(64 citation statements)

References 33 publications

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“…In our study, pharmacists provided interventions aimed at improving the use of antibiotics by suggesting "drug change I3.1" or "dosage change I 3.2" through participation in clinical rounds, consultations, and case discussions. When treating hospitalized COPD patients, providers and pharmacists should consider the effect of renal function on the pharmacodynamics and pharmacokinetics of drugs to avoid the occurrence of DRPs [25,26], and pharmacists play an important role in the rational use of antibiotics given their specialized training in pharmacotherapy [27].…”

Section: Discussionmentioning

confidence: 99%

Drug-related problems among hospitalized patients with COPD in mainland China

Qin

et al. 2019

Int J Clin Pharm

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Background Data are lacking about the extent of drug-related problems in hospitalized patients with COPD in China. Objective Identify types and causes of drug-related problems and assess interventions performed by pharmacists. Setting Study was conducted in an academic teaching hospital in Shanghai, China. Method Between June 2017 and July 2018, 393 patients admitted to hospital for acute exacerbation of COPD hospitalized were enrolled. Patient demographics and clinical characteristics were collected. The drug-related problems and interventions were recorded and analyzed based on the Pharmaceutical Care Network Europe (PCNE)-DRP V 8.02 classification. Main outcome measures The number, types, causes, interventions, and outcomes of the problems were analyzed. Results A total of 640 DRPs, with 763 corresponding causes, were identified for 393 patients. "Treatment safety P2" was the most common type of problem (54.2%; 347/640), and the most common causes were "drug selection C1" (24.2%; 185/763), "dose selection C3" (21.5%; 164/763) and "treatment duration C4" (17.7%; 135/763). Antibiotics, corticosteroids, and proton pump inhibitors were the three primary medication classes associated with DRPs. Patients, hospitalized for more than eight days, taking ten or more drugs or having renal dysfunctions were more likely to have drug-related problems. Pharmacists totally proposed 1557 interventions to address the problems. Most interventions (91.0%; 1418/1557) were accepted, and 91.6% of the problems were solved. Conclusion The prevalence of drug-related problems among the studied COPD patients was high. Pharmacists can have an important role in addressing the problems and optimizing the safety and effectiveness of therapies for hospitalized COPD patients.

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Section: Discussionmentioning

confidence: 99%

Drug-related problems among hospitalized patients with COPD in mainland China

Qin

et al. 2019

Int J Clin Pharm

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“…As a consequence, authors have been compelled to create their own definitions, generally based on their research objectives and method. In addition, we identified five studies that did not utilize the term medication discrepancy when describing the medication reconciliation process [24,30,[44][45][46], but instead used the terms 'DRPs or medication-related problems', 'inappropriate medication', 'prescribing error' and 'transcribing error'. It is noteworthy that the term 'medication error' has been used interchangeably with 'medication discrepancy' in several studies [40,[47][48][49][50][51][52][53][54][55][56][57].…”

Section: Discussionmentioning

confidence: 99%

The medication reconciliation process and classification of discrepancies: a systematic review

Almanasreh

Moles

Chen

2016

Brit J Clinical Pharma

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We suggest that clear and consistent information on prevalence, types, causes and contributory factors of medication discrepancy are required to develop suitable strategies to reduce the risk of adverse consequences on patient safety. Therefore, to obtain that information, we need a well-designed taxonomy to be able to accurately measure, report and classify medication discrepancies in clinical practice.

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“…Staff in healthcare units should therefore be given clear guidance on medication administration, including orientation on the subject . Promoting medication safety requires also precise and exact error reporting , documentation of medication events , teamwork and consistent checking of patients' medication during transitions . A culture of good teamwork promotes error reporting , learning from errors and continuous quality improvement .…”

Section: Medication Safetymentioning

confidence: 99%

“…Medication safety therefore requires nurses to have knowledge about medicines and to be motivated to engage in lifelong learning about medication . To administer medication safely, nurses must consider the patient's age and polypharmacy , drug allergies , engage in patient educating and counselling and encourage the patient to engage with their own medication . It is important to recognise the risk of confusion between medicines and their packaging and the functionality of the space in which medications are handled .…”

Section: Medication Safetymentioning

confidence: 99%

The relationship between nurse manager's transformational leadership style and medication safety

Lappalainen

Härkänen

Kvist

2019

Scandinavian Caring Sciences

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Aim To describe medication safety, transformational leadership and their relationship as evaluated by Registered Nurses. Background Medication safety is one of the aspects of patient safety and an important part of nurses' daily practices. Nurse managers can ensure medication safety by adopting a transformational leadership style. However, little evidence exists regarding how transformational leadership relates to medication safety. Methods Data were collected from Registered Nurses (n = 161) in three Finnish hospitals in May 2016 using an electronic questionnaire incorporating the Transformational Leadership Scale (TLS) and Medication Safety Scale (MSS). Data were analysed using statistical analyses including descriptive analyses, principal component analysis and multivariate analyses. STROBE reporting guidelines were followed (see Appendix ). Findings Nurses evaluated medication safety and transformational leadership in their units to be excellent and good, respectively. There was a moderate but statistically significant correlation between transformational leadership and medication safety. The medication competence of nurses and the management of nursing processes were significantly related to medication safety. Conclusions Nurse managers' transformational leadership style can promote medication safety in units. The medication competence of nurses must be addressed because assurance and confidence in their own expertise in pharmacotherapeutic tasks positively affects their perceptions of medication safety.

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Analysis of drug-related problems in three departments of a German University hospital

Cited by 60 publications

References 33 publications

Drug-related problems among hospitalized patients with COPD in mainland China

Drug-related problems among hospitalized patients with COPD in mainland China

The medication reconciliation process and classification of discrepancies: a systematic review

The relationship between nurse manager's transformational leadership style and medication safety

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