Under traditional technical conditions, the cold chain (warehousing, transportation, and retail) model is becoming increasingly mature, and the market is becoming saturated. Industry development has many pain points, and technological innovation is always the biggest driving force for breakthroughs. There are practical applications of phase change materials in cold chain logistics in China. The material has the advantages of stable temperature maintenance, is non-toxic and harmless, and can achieve cold storage refrigeration during transportation, reducing carbon emissions. In the case of overcoming technical difficulties, how to widely apply it in the field of cold chain logistics requires a reliable model to support it. This research will be based on the specific practice of existing applications of phase change materials in Jiangsu Province, taking the Yangtze River Delta region as an example, analyzing the advanced cold chain logistics network layout of existing super-large cities, and providing market access to advanced technologies for global urban agglomerations. and regional model layout ideas.