2010
DOI: 10.1016/j.cyto.2010.02.016
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Analysis of eotaxin 1/CCL11, eotaxin 2/CCL24 and eotaxin 3/CCL26 expression in lesional and non-lesional skin of patients with atopic dermatitis

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Cited by 41 publications
(25 citation statements)
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“…Among the 100 most dramatically upregulated genes, we found that the mRNA level of the T H 2 chemokine CCL26, which might be involved in the pathogenesis of AD, 35,36 was significantly upregulated by the addition of IL-4/IL-13 (see Table E1 in this article's Online Repository at www.jacionline.org, rank 2). It has been reported that the production of CCL26 is induced by T H 2 cytokines in cells of the keratinocyte cell line HaCaT.…”
Section: Resultsmentioning
confidence: 95%
“…Among the 100 most dramatically upregulated genes, we found that the mRNA level of the T H 2 chemokine CCL26, which might be involved in the pathogenesis of AD, 35,36 was significantly upregulated by the addition of IL-4/IL-13 (see Table E1 in this article's Online Repository at www.jacionline.org, rank 2). It has been reported that the production of CCL26 is induced by T H 2 cytokines in cells of the keratinocyte cell line HaCaT.…”
Section: Resultsmentioning
confidence: 95%
“…IL-4 binding to either receptor mediates the phosphorylation and dimerization of the Signal Transducer and Activator of Transcription 6 (STAT6), regulating transcriptional activation of genes in target cells 9 . Keratinocytes exposed to IL-4 exhibit reduced expression of Epidermal Differentiation Complex (EDC) genes 13 , decreased expression of defensins 3 , altered expression of keratins 14 , and increased production of the chemokine CCL26 (eotaxin 3) 15 .…”
Section: Introductionmentioning
confidence: 99%
“…CCR3 is mainly presented on eosinophils, and is also found on basophils, monocytes, Th2 lymphocytes, epithelial cells as well as airway smooth muscles (Zhebrun et al 2014). Thus, CCL24 is considered a contributor to kinds of atopic disorders, parasitic infections and numerous systemic diseases (Owczarek et al 2010, Kinoshita et al 2012.…”
Section: Introductionmentioning
confidence: 99%