Compared to control bandwidth, low-frequency uncertainties or disturbances like step signals can be well rejected by many methods having two-degree-of-freedom (2-DOF). Due to robustness constraint, technically more challenging is the rejection of medium frequencies, especially for bandwidth-limited systems. Here, the equivalent-input-disturbance (EID) approach is extended to deal with the main medium-frequency oscillation of a pantograph-catenary system. First, a general EID estimator is developed with a lowfrequency estimator as a special case. Then, a fair comparison is conducted to clarify the essential differences between the conventional 1-DOF-based and the developed 2-DOFbased control systems. Furthermore, a robust stability condition is derived for the 2-DOFbased closed-loop control system. A design algorithm together with design guidelines is provided, where the frequency characteristics of the uncertainties are utilized in the parameter design. Finally, simulations are carried out to validate the developed 2-DOF-based method for the pantograph-catenary system in realistic environment.