Each region has sector advantages that can contribute to economic growth. This research is entitled Analysis of Leading Sectors in Wonogiri Regency for 2015-2020. The purpose of this research is to find out the potential of the leading sectors in the Wonogiri district in 2015-2020, and it is hoped that it will be able to find out the areas that have advantages so that they can develop these leading sectors. This study uses shift-share analysis. The sector with the highest value is the agricultural sector, followed by the transportation and warehousing sector, the mining and quarrying sector, the education services sector, the other services sector, the wholesale and retail trade sector, the health services sector, and social activities, the corporate services sector, the financial services sector and insurance, government administration sector, and finally the sector of water supply, waste management, waste, and recycling. The data used in this study are the gross regional domestic product (GRDP) of Wonogiri district and the gross regional domestic product (GRDP) of Central Java province at constant prices for the 2015-2020 period. The analytical tools used are LQ and shift share.