Analysis of Folate by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

doi:10.5012/bkcs.2003.24.9.1308

Cited by 9 publications

(1 citation statement)

References 22 publications

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“…Graphite as matrix was also used for the analysis of tetracycline, polymeric materials, such as triterpenoid resins and varnishes, − and low molecular weight poly(methylsilsesquioxane)s . The use of solid graphite targets has also been described previously. − …”

Section: Introductionmentioning

confidence: 99%

Pencil Lead as a Matrix for MALDI-ToF Mass Spectrometry of Sensitive Functional Polymers

et al. 2007

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With the increase in complexity of functional polymers in recent years, MALDI-ToF has become an important tool for gaining precise information on polymer functionality, end groups, and, in special cases, molecular weights. Here we describe how pencil lead, deposited by simply drawing with a regular pencil onto conventional MALDI-ToF targets, can be used as a very attractive matrix for MALDI-ToF mass spectrometry of synthetic polymers. Highly sensitive polymers such as silyl hydride functional poly(styrene), poly(butadiene), and poly(isoprene) have been investigated using conventional MALDI-ToF matrices as well as pencil lead. In all cases, the use of pencil lead prevented oxidation of the highly sensitive silyl hydride end groups. It is shown that pencil lead represents an interesting alternative to the commonly used matrices in the range between 400 and 6000 g/mol due to the convenient way of deposition, its low cost, nontoxicity, and chemical inertness under sample preparation conditions.

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Section: Introductionmentioning

confidence: 99%

Pencil Lead as a Matrix for MALDI-ToF Mass Spectrometry of Sensitive Functional Polymers

et al. 2007

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Current literature in mass spectrometry

2004

J. Mass Spectrom.

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of mass spectrometry. Each bibliography is divided into 11 sections: 1 Books, Reviews & Symposia; 2 Instrumental Techniques & Methods; 3 Gas Phase Ion Chemistry; 4 Biology/Biochemistry: Amino Acids, Peptides & Proteins; Carbohydrates; Lipids; Nucleic Acids; 5 Pharmacology/Toxicology; 6 Natural Products; 7 Analysis of Organic Compounds; 8 Analysis of Inorganics/Organometallics; 9 Surface Analysis; 10 Environmental Analysis; 11 Elemental Analysis. Within each section, articles are listed in alphabetical order with respect to author (4 Weeks journals ‐ Search completed at 17th. Mar. 2004)

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The use of pencil lead as a matrix and calibrant for matrix‐assisted laser desorption/ionisation

Black

Poile

Langley

et al. 2006

Rapid Comm Mass Spectrometry

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Pencil lead is shown to be an effective matrix and calibrant in matrix-assisted laser desorption/ionisation (MALDI) mass spectrometry. Various groups of analytes, including peptides, polymers and actinide metals, can be readily ionised using MALDI when deposited onto a pencil lead matrix. The matrix is seen to have advantages in sample preparation relating to its hydrophobic properties and almost complete suppression of the matrix during analysis. Using pencil lead as a matrix is a quick and convenient method of qualitative analysis and has been shown to be quantitative for the isotope ratio analysis of actinide metals.

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Analysis of Folate by Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry

Cited by 9 publications

References 22 publications

Pencil Lead as a Matrix for MALDI-ToF Mass Spectrometry of Sensitive Functional Polymers

Pencil Lead as a Matrix for MALDI-ToF Mass Spectrometry of Sensitive Functional Polymers

Current literature in mass spectrometry

The use of pencil lead as a matrix and calibrant for matrix‐assisted laser desorption/ionisation

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