Analysis of gastroscopy results among healthy people undergoing a medical checkup: a retrospective study

Abstract

Background The association of upper gastrointestinal endoscopic findings with sex, age, and Helicobacter pylori infection in asymptomatic healthy people is unclear. The aim of this study was to retrospectively determine the associations of upper gastrointestinal endoscopic findings in asymptomatic healthy people with sex, age, and H. pylori infection. Methods A retrospective study was conducted on 2923 patients from a health examination center in Xiangya Hospital between September 2015 and September 2019. Data on sex, age, H. pylori infection, and gastroscopy results were collected. Results Among 2923 asymptomatic patients who underwent gastroscopy, 2911 (99.59%) had abnormal results. The top three results were chronic gastritis (95.11%), peptic ulcer (17.45%), and duodenitis (9.17%). Inflammation of the gastric mucosa in chronic gastritis was more severe in the H. pylori-positive group. The incidence of peptic ulcer decreased with increasing age and was higher in men, patients aged < 30 years, and H. pylori-positive patients. The incidence of polyps was higher in women (9.54%) than in men (5.94%), and the incidence in individuals aged ≥60 years (11.63%) was higher than that in those aged < 60 years (6.83%). The pathological results of gastric polyps depended on the location of the lesion. Conclusion The incidence of abnormal upper gastrointestinal endoscopic results is high in asymptomatic healthy people undergoing a check-up and is associated with sex, age, and H. pylori infection. Gastroscopy should be considered part of a routine health check.

Clinical practice of Helicobacter pylori infection management by gastroenterologists in secondary and tertiary hospitals: A stratified sampling cross‐sectional survey

“…First, H. pylori-positive individuals tend to have more severe gastritis than H. pylori-negative individuals, and their proportion of peptic ulcers is also higher. 34 Endoscopic manifestations provide endoscopists with a distinct visual impact of the harmful effects of H. pylori infection. Second, RUT has become a widely used invasive method in H. pylori detection.…”

Dose–Effect Relationship Between Gastric Cancer and Common Digestive Tract Symptoms and Diagnoses in Anhui, China

“…In contrast to the above mentioned relations, our study found an independent decreasing trend in the risk of GC among participants with increasing time difference from the first reported diagnosis of chronic gastritis. This may be attributed mainly to the following: a) respondents without reported diagnosis of chronic gastritis may not necessarily be free from the disease since a large part of them had never underwent gastro-endoscopic examinations; 36 , 37 b) people with functional gastrointestinal disorders are more likely to seek help from clinicians and thus have greater chances to have earlier diagnosis or even misdiagnosis of chronic gastritis. 38–41 Compared with chronic gastritis, diagnosis of H. pylori infection is much more convenient, cheaper and popular in China.…”

Guidelines for diagnosis and treatment of chronic gastritis inChina(2022,Shanghai)

“…Carabotti et al found no difference in dyspeptic symptoms between patients with antrum‐restricted gastritis and those with pangastritis ( P > 0.05) 48 . Huang et al reported that 99.59% of the asymptomatic subjects who underwent gastroscopy had abnormal results, and the majority of them (95.11%) had chronic gastritis 49 …”

“…48 Huang et al reported that 99.59% of the asymptomatic subjects who underwent gastroscopy had abnormal results, and the majority of them (95.11%) had chronic gastritis. 49 H. pylori gastritis is the predominant form of chronic active gastritis in young and middle-aged patients. 15 Among elderly patients, in addition to H. pylori infection, NSAIDs, long-term bile reflux, and other physical and chemical injuries may lead to chronic gastritis in the elderly, and there are more symptomatic patients compared to young and middle-aged patients.…”