Analysis of global systolic and diastolic left ventricular performance using volume-time curves by real-time three-dimensional echocardiography

Zeidan, Ziad; Erbel, Raimund; Barkhausen, Joerg; Hunold, Peter; Bartel, Thomas; Buck, Thomas

doi:10.1067/mje.2003.40

Cited by 104 publications

(86 citation statements)

References 30 publications

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“…Our present study is the first to test the hypothesis that direct detection of the endocardial surface in the 3D domain could allow accurate continuous measurement of global and regional LV volumes throughout the cardiac cycle. Compared with a previous study by Zeidan and colleagues, 12 who studied LV volume-time …”

Section: Discussionmentioning

confidence: 99%

“…For each subject, global ESV and EDV were extracted from the global LV volume-curves as the minimum and maximum values, respectively, and used to calculate the EF. Peak ejection rate and peak rapid and atrial filling rates were calculated from the time derivative of the global LV volume curve 12 and normalized by end-diastolic volume. In addition, ISA and RSF were computed for each subject.…”

Section: Protocolmentioning

confidence: 99%

“…10,11 However, analysis procedures applied to 3D data did not fully exploit the volumetric information, because they were still based on tracing of endocardial boundaries on selected planes and on geometric modeling. 12 Because modeling may be inaccurate under certain conditions, the use of information limited to 2 dimensions renders this procedure subject to many of the same limitations as the techniques used to analyze 2DE images. Moreover, the information on regional wall motion contained in 3D data sets has thus far been studied only by use of visual interpretation of selected planes 13,14 or by quantification of model-based, interpolated endocardial surfaces, 15 rather than by quantifying the displacement of the true endocardial surface detected in 3D space.…”

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confidence: 99%

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Volumetric Quantification of Global and Regional Left Ventricular Function From Real-Time Three-Dimensional Echocardiographic Images

et al. 2005

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Background-Real-time 3D echocardiographic (RT3DE) data sets contain dynamic volumetric information on cardiac function. However, quantification of left ventricular (LV) function from 3D echocardiographic data is performed on cut-planes extracted from the 3D data sets and thus does not fully exploit the volumetric information. Accordingly, we developed a volumetric analysis technique aimed at quantification of global and regional LV function. Methods and Results-RT3DE images obtained in 30 patients (Philips 7500) were analyzed by use of custom software based on the level-set approach for semiautomated detection of LV endocardial surface throughout the cardiac cycle, from which global and regional LV volume (LVV)-time and wall motion (WM)-time curves were obtained. The study design included 3 protocols. In protocol 1, time curves obtained in 16 patients were compared point-by-point with MRI data (linear regression and Bland-Altman analyses). Global LVV correlated highly with MRI (rϭ0.98; yϭ0.99xϩ2.3) with minimal bias (1.4 mL) and narrow limits of agreement (Ϯ20 mL). WM correlated highly only in basal and midventricular segments (rϭ0.88; yϭ0.85xϩ0.7).In protocol 2, we tested the ability of this technique to differentiate populations with known differences in LV function by studying 9 patients with dilated cardiomyopathy and 9 normal subjects. All calculated indices of global and regional systolic and diastolic LV function were significantly different between the groups. In protocol 3, we tested the feasibility of automated detection of regional WM abnormalities in 11 patients. In each segment, abnormality was detected when regional shortening fraction was below a threshold obtained in normal subjects. The automated detection agreed with expert interpretation of 2D WM in 86% of segments. Conclusions-Volumetric

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Section: Discussionmentioning

confidence: 99%

Section: Protocolmentioning

confidence: 99%

mentioning

confidence: 99%

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Volumetric Quantification of Global and Regional Left Ventricular Function From Real-Time Three-Dimensional Echocardiographic Images

et al. 2005

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“…The present study used TRPG to determine the changes in pulmonary artery pressure, while Arcasoy et al (2003) showed that the correlation coefficient between ultrasonography and right heart catheterization to measure pulmonary artery systolic pressure was 0.69, and reported the sensitivity of ultrasonography as 85%, with a specificity of 55%. In normal left ventricular VTCs (Zeidan et al, 2003), the deeper the trough the greater the stroke volume and the greater the difference between end-diastolic and end-systolic volume, which is reflected by the heart effectively pumping out more blood. In general, the right ventricle acts only as a channel, but from the view of the right ventricle VTCs, the right ventricle also plays a part in the pumping of blood.…”

Section: Discussionmentioning

confidence: 99%

Using volume-time curves with real-time three-dimensional echocardiography to analyze right ventricular function in patients with pneumoconiosis

Wei¹,

Ding²,

He³

2014

Genet. Mol. Res.

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ABSTRACT.We evaluated right ventricular function in patients with pneumoconiosis using real-time three-dimensional echocardiography (RT3DE). A total of 80 consecutive patients were prospectively recruited, 44 of whom were diagnosed with pneumoconiosis, and the remaining 36 age-and gender-matched healthy volunteers served as the control group. All patients underwent both 2D and 3DE. The tricuspid regurgitation pressure (TRPG), right ventricular anterior wall thickness and range of motion, right ventricular posterior wall thickness and range of motion, right ventricular end-diastolic volume, right ventricular endsystolic volume, and right ventricular ejection fraction (RVEF) were measured. The RVEF of healthy volunteers ranged from 50 to 78%, while the RVEF of pneumoconiosis patients ranged from 29 to 73%. TRPG influenced RVEF by 77.3% (P = 0.006) and showed a negative correlation (r = -0.643, P < 0.01). Volume-time curves (VTC) of patients with pneumoconiosis showed more troughs (low stroke volumes) than the VTCs of normal subjects. Evaluation of right ventricular function in patients with pneumoconiosis using RT3DE can provide additional clinical information.

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“…A PFR normalised to EDV of less than 2.5 EDV/s was considered abnormal [14][15][16]. This analysis was repeated using a PFR normalised to the stroke volume (SV), with a PFR less than 4 SV/s considered abnormal [17,18].…”

Section: Prevalence Of Diastolic Dysfunctionmentioning

confidence: 99%

Cardiovascular magnetic resonance imaging assessment of diastolic dysfunction in a population without heart disease: a gender-based study

et al. 2013

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Objectives Asymptomatic left ventricular (LV) diastolic dysfunction is increasingly recognised as an important diagnosis. Our goal was to study the prevalence and gender differences in subclinical LV diastolic dysfunction, using cardiovascular magnetic resonance imaging (CMR) at 3 T. Methods We prospectively studied 48 volunteers (19 male and 29 female, mean age 49±7 years) with no evidence of cardiovascular disease. We used CMR to measure left atrium (LA) and LV volumes, LV peak filling rate and transmitral flow.Results The overall prevalence of LV diastolic dysfunction in our cohort varied between 20 % (based on evaluation of LV filing profiles) and 24 % (based on the evaluation of the transmitral flow). The prevalence of diastolic dysfunction was higher in men than in women, independently of the criteria used (P between 0.004 and 0.022). Indexed LV end-diastolic volume, indexed LV stroke volume, indexed LV mass, indexed LA minimum volume and indexed LA maximum volume were significantly greater in men than in women (P<0.05). All the subjects had LV ejection fractions within the normal range. Conclusions It is clinically feasible to study diastolic flow and LV filling with CMR. CMR detected diastolic dysfunction in asymptomatic men and women. Key Points • CMR imaging offers new possibilities in assessing left ventricular diastolic function.• The prevalence of diastolic dysfunction is higher in men than in women.• The prevalence of some diastolic dysfunction in a normal population is 24 %.

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Analysis of global systolic and diastolic left ventricular performance using volume-time curves by real-time three-dimensional echocardiography

Cited by 104 publications

References 30 publications

Volumetric Quantification of Global and Regional Left Ventricular Function From Real-Time Three-Dimensional Echocardiographic Images

Volumetric Quantification of Global and Regional Left Ventricular Function From Real-Time Three-Dimensional Echocardiographic Images

Using volume-time curves with real-time three-dimensional echocardiography to analyze right ventricular function in patients with pneumoconiosis

Cardiovascular magnetic resonance imaging assessment of diastolic dysfunction in a population without heart disease: a gender-based study

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