In the paper, a simulation-based design procedure for the implementation of a TEM (Crawford) cell is presented. The empirical approach uses computer simulations carried out in CST Microwave Studio to design the cell that operates in the frequency range from 100 kHz to 400 MHz. Following the developed procedure, the TEM cell was implemented and tested experimentally. The TEM cell can be used for electromagnetic susceptibility (EMS) measurements, where the device under test (DUT) is irradiated by the field in a wide range of frequencies. The DUT is tested to operate without the performance degradation under the influence of electromagnetic disturbances. In addition, the cell can be used for electromagnetic interference (EMI) measurements focused on interference emissions generated by the DUT.