Analysis of Hiv Subtypes and Clinical Staging of Hiv Disease/Aids in East Java

Ismail, Yulia Sari; Soetjipto, Soetjipto; Wasito, Eddy Bagus; Nasronudin, Nasronudin

doi:10.20473/ijtid.v3i2.204

Cited by 1 publication

(1 citation statement)

References 14 publications

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“…The research in East Java identifying 30 samples of HIV-1 subtypes showed that the subtypes found were mostly a group of Circulating Recombinant Forms similar to those found in Southeast Asia. 20 Besides that, the virological failure is also known to be determined by an increase in CD4 levels. An increase in CD4 by <50 cells/mm is an independent predictor of virological failure in HIV patients receiving the first-line ARV therapy with a good level of medication adherence.…”

Section: Discussionmentioning

confidence: 99%

The Adherence to Fixed-Dose Combination Antiretroviral Therapy and Viral Load in HIV Patients

Auliannissa

Bustamam

Ningsih

2020

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Antiretroviral fixed-dose combination (FDC ARV) has been used in HIV patient therapy. The therapy is recommended to be monitored using a viral load (VL), reflecting the amount of HIV in the blood. Since 2015, the VL testing has been carried out at Pengayoman Cipinang Hospital. However, the evaluation of adherence to the FDC antiretroviral therapy on VL has never been conducted. This study aims to determine the relationship between the adherence level to the FDC ARVs and VL at Pengayoman Cipinang Hospital in 2015-2018. The study used a cross-sectional design and a random sampling technique. The sample size was 70, and data generated from the medical record. Kruskal Wallis test showed no differences in the level of adherence in the group based on gender, education level, marital status, employment status, and the risk factor for HIV. However, there was a significant difference in the age group. Cross-tab data showed virological failure (VL> 400 copies/ml) was found in 1.8% of patients with good adherence, 75% of patients with moderate adherence, and 100% of patients with poor adherence. The Chi-square test showed a significant relationship between adherence to FDC ARV and VL (p=0.000). It can be concluded that there was a significant relationship between the level of adherence in taking ARV FDC and viral load.

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Section: Discussionmentioning

confidence: 99%