Surface fluxes and their related processes and states tend to recur and remain consistent across various spatial and temporal scales forming patterns. For multiple applications, identifying spatio-temporal patterns is desirable, as they provide information about the dynamics of the processes involved. This is especially true for land surface temperature, a key variable that plays a primary role in the energy and water exchange between land and atmosphere. This study introduces the Empirical Spatio-Temporal Covariance Function (ESTCF) as a tool to identify and characterize spatio-temporal patterns in remotely sensed land surface temperature fields. The method is demonstrated over the Contiguous United States by splitting the entire area into 1.0°x1.0° domains. The summer day-time surface temperature ESTCFs are derived for each domain, and a parametric covariance model is fitted. Clustering analysis is then applied to detect areas with similar spatio-temporal land surface temperature dynamics. The results are assessed to determine if particular spatio-temporal features are present in domains where landscape characteristics make interactions with the atmosphere likely. The proposed tool accurately characterizes the spatio-temporal interdependence of the fields, summarizing features such as spatio-temporal variance, spatial coherence structure, temporal persistence, and space-time interactions. The increased temporal persistence and space-time interaction drive the grouping in mountainous and coastal domains. The tools introduced here provide a pathway to formally identify and summarize the spatio-temporal patterns observed in remotely sensed fields and relate those to more complex processes within the Soil-Vegetation-Atmosphere System.