Surgically assisted rapid palatal expansion (SARPE) is a successful method for treating transverse discrepancies in adult patients. The relocation of maxillary segments may induce changes at the surrounding soft tissues as well. The aim of this systematic review was to examine the possible effects that SARPE may have in the soft tissues of the face. Our search strategy included electronic databases (Pubmed, Scopus, ProQuest, Google Scholar, Cochrane Library) and a hand search of the reference list of found reviews. A priori definition of inclusion and exclusion criteria was made. Finally, 15 articles were included in qualitative synthesis. Risk of bias was generally high among the included studies. Study outcomes included nasal, labial, nasolabial and other facial soft tissue measurements. The evaluation of the changes was two-dimensional in six studies, and three-dimensional in nine studies. Meta-analysis was unfeasible due to lack of standardization, important methodological limitations, and shortcomings of the studies. A post-surgical increase in the dimensions of the alar width and the alar base width was commonly reported among the included studies. However, the above should be considered with caution due to the high risk of bias and the inability for quantitative synthesis.