Analysis of inelastic interactions for therapeutic proton beams using Monte Carlo simulation

Abstract

Abstract-The irradiation of various tissue-like materials by therapeutic proton beams was simulated using Monte Carlo. The contribution of inelastic reaction products to the depth-dose distribution was determined. The use of silicon microdosimeters for verifying Monte Carlo calculations was also investigated. The importance of these studies to Monte Carlo-based treatment planning systems is emphasized.

Tissue Equivalence Correction in Silicon Microdosimetry for Protons Characteristic of the LEO Space Environment

“…A Geant4 capability for microdosimetry has been the subject of study in recent years and its accuracy in reproducing physical results with respect to experimental measurements is still a subject of ongoing investigation. Previous work has demonstrated good S agreement between Geant4 simulations and experimental data in the context of microdosimetry [11][12][13].…”

Microdosimetry simulations of solar protons within a spacecraft

“…It is well established [13] that solar protons can penetrate much deeper into the magnetosphere than predicted by the simple attenuation model. As the case ignoring geomagnetic shielding was considered a worse-case scenario it would be utilized as the incident proton radiation spectra for our GEANT4 simulations.…”

“…This provided the most accurate composition available and was obtained from an ICRU based program [8]; many of these compositions have been published elsewhere [13], [16]. The geometry was created utilizing right-angled parallelepiped (RPP) volumes depicting the spacecraft shield and layered homogeneous biologically important phantoms contained within the shield (Fig.…”

Response of a SOI Microdosimeter to a /sup 238/PuBe Neutron Source

“…For the same primary radiation spectra the secondaries spectra and particle type can vary considerably in different organs [10]. This will lead to a change in the microdosimetric spectra as was recently demonstrated [11].…”

“…The SOI microdosimeter device is based on an array of p-n junctions, (or cells), each with a planar area of 10 The advantage of the SOI microdosimeter over TE gas chambers for microdosimetric measurements is the small size and weight, and the low voltage of operation (5-10 V). The charge collection in a single cell of the SOI microdoismeter and the chord length distribution for various sensitive volumes (SV) was studied previously [3].…”