We investigate the strong vertices among the Λ b , nucleon, and B meson as well as the Λ c , nucleon, and D meson in QCD. In particular, we calculate the strong coupling constants g Λ b NB and g Λ c ND for different Dirac structures entering the calculations. In the case of the Λ c ND vertex, we compare the result with the only existing prediction obtained at Q 2 ¼ 0.