For single radar tracking, Kalman filter (KF) can be used only when radar measurements have Gaussian white noises. However, when systematic biases exist, application of KF for single radar tracking is not trivial. Furthermore, in the existing radar network, the association (both measurement-to-measurement and measurement-to-track) problem and the systematic biases removal are mixed together, which further complicates radar network data fusion. The key to solving these problems is to find and apply a set of mathematical tools (quaternionic analysis) on the biased measurements to directly enable the application of KF. This paper provides a detailed discussion of quaternionic analysis that can be applied to solve this problem. Measurement frame (MF) is proposed where target states contain radar systematic biases. It is proved that for stationary and first kind of mobile radar (installed on gyro-stabilized platform) target kinematic model (TKM) in MF has the same form with that in East-North-Up (ENU) frame. And KF can be used directly for the biased measurements to obtain the biased target track in the sense of minimum mean square error (MMSE). However, for the second kind of mobile radars (rigidly connected and sways with platform), a first-order approximation yields large errors therefore they (or second kind of mobile radars) cannot be applied well when attitude biases are greater than 1°. This situation will be investigated and discussed further in future publications.