Analysis of neonatal heart rate variability by a microprocessor-based on-line system

Long-term variability (LTV) of heart rate was calculated continuously by a microprocessor in 25 preterm infants undergoing indomethacin treatment for closure of patent ductus arteriosus (PDA), in 24 preterm infants without signs of PDA, and in 10 neonates treated with prostaglandin E₁ for cyanotic heart malformation. In infants with patent ductus arteriosus, LTV was lower than in controls. Following indomethacin, LTV increased most markedly (from 1.5 to 3.2; p < 0.01) in infants with improved ventilation. The increase was less marked (from 1.8 to 2.5; p < 0.05) in infants whose degree of respiratory failure did not change. LTV remained largely unchanged in infants who deteriorated. In 9 out of the 10 neonates treated with prostaglandin E₁, LTV increased. We conclude that LTV corresponds to brain stem oxygenation and may be a useful tool to monitor treatment of PDA.

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“…For clinical use, quantif ication of HRV by indices is more feasible [12,13,20]. Several indices have been de scribed.…”

Section: Discussionmentioning

confidence: 99%

Long-Term Variability of Heart Rate Increases with Successful Closure of Patent Ductus arteriosus in Preterm Infants

Prietsch

Maier²,

Schmitz³

et al. 1992

Neonatology

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Continuous monitoring of heart rate variability in preterm infants

Prietsch

Knoepke²,

Obladen

1994

Early Human Development

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1986

Journal of Perinatal Medicine

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Abdominal fetal electrocardiography (AFECG) as a means of intrapartum fetal heart rate (FHR) monitoring was studied in 700 consecutive labors in a small hospital. Sixty-eight pregnancies were excluded from the study because of the elective cesarean section or because labor was too short for electronic monitoring. AFECG succeeded (at least 30% of fetal heart intervals obtained) throughout labor in 99 of 632 monitored labors (16%). Ultrasound was needed in six cases (1%). The rest (527) were monitored first with the use of AFECG, and later with the use of direct FECG. The mean beat-to-beat variation of FHR (differential index) during last two hours of labor measured from AFECG signal was similar to that measured from AFECG and direct FECG. Hence the same reference values of the differential indices for both methods can be used. The mean long term variation (interval index) measured from AFECG was lower than that measured from abdominal and direct FECGs consecutively. Ultrasound is rarely needed during labor, and it should be avoided except in breech presentations, in association with low placentas and twins, if recording of AFECG fails.

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Analysis of neonatal heart rate variability by a microprocessor-based on-line system

Cited by 3 publications

References 9 publications

Long-Term Variability of Heart Rate Increases with Successful Closure of Patent Ductus arteriosus in Preterm Infants

Long-Term Variability of Heart Rate Increases with Successful Closure of Patent Ductus arteriosus in Preterm Infants

Continuous monitoring of heart rate variability in preterm infants

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