Analysis of partial Y chromosome microdeletions and NGS data in Lithuanian infertile men
Roberta Čižaitė,
Gabrielė Žukauskaitė,
Birutė Tumienė
Abstract:Infertility is a complex pathological condition that affects the male population worldwide. Male infertility is often caused by changes in the morphology and number of spermatozoa. Many of infertility cases remain unexplained, genetic causes are being discovered, including changes in chromosomes and single genes. While Y chromosome microdeletions are the most common cause of spermatogenesis disorders, failure to identify them leads to the search for new candidate genes, de novo pathogenic genomic variants asso… Show more
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