Analysis of peripheral artery velocity tracing in a porcine model

Abstract

BackgroundThe aim of the study was to trace the peripheral artery velocity with ultrasound in pigs and provide inference on diagnosis of the type, location and severity of vascular diseases.Materials and methodsLimb tightening, adrenaline administration and arterial wall pinching were performed independently in six pigs, and then the evolution of the external iliac artery or femoral artery velocity tracing were monitored.ResultsWith the increase of the extents of hindlimb tightening, peak systolic velocity (PSV) of ipsilateral external iliac artery turned from 36.33±1.77 cm/s to 59.72±2.67 cm/s, minimum post-principal wave velocity (MPV from 13.68±1.11 cm/s to −7.48±0.82 cm/s, peak diastolic velocity (PDV) from 19.31±0.86 cm/s to 8.98±0.45 cm/s, and, end diastolic velocity (EDV) from 13.2±0.45 cm/s to 0. With the increase of the dose of the epinephrine injection, PSV increased from 36.33±1.77 cm/s to 43.97±2.15 cm/s but then decreased to 35.43±3.01 cm/s, and MPV negatively increased to −23.53±0.82 cm/s after decreasing from 13.68±1.11 cm/s to 0. PDV and EDV gradually decreased to zero. With the increase of the stenosis severity in the abdominal aortic wall pinching, PSV was reduced and had a linearly negative correlation with the stenosis severity (R=0.983, R2=0.967). MPV gradually increased, and its direction reversed when the stenosis severity increased, then diminished when the blood flow was occluded by more than 2/3.ConclusionsThe formation of peripheral artery velocity is the result of concurrent effects of cardiac ejection, vascular resistance, effective circulating blood volume and elastic recoil. Vascular resistance exerts pronounced effects on the diastolic waveform, and the occurrence of backward wave indicates that the downstream circulation resistance significantly increases.

Fluctuating portal velocity tracing with rhythmicity: ultrasonic differential diagnosis and clinical significance

“… 13 Ultrasound (US) analysis, which is dynamic, noninvasive, economical, and convenient, can examine blood vessels in every direction. 14 The haemodynamics determined from the velocity tracings detected via US can easily be analysed 15 , but a detecting diagnostic procedure that can be applied during routine examinations has yet to be properly defined. The present study was performed to determine the usefulness of the routine evaluation of portal velocity tracings, in combination with those of the hepatic artery and vein, for APF and CTS diagnosis.…”