Analysis of phenylephrine hydrochloride in pharmaceutical formulations and biological fluids using (2,2′-bipyridyl)ruthenium(ii)-peroxydisulphate chemiluminescence system in a two-chip microdevice

Chemiluminescence selectivity enhancement in the on‐chip Ru(bpy)32+ system: The potential role of buffer type and pH in the determination of hydrochlorothiazide in combined formulations and human plasma

“…Pharmaceutical compounds having secondary and tertiary aliphatic amines in their molecular structure such as ciprofloxacin (CIP), codeine (COD), buspirone (BUS), fexofenadine (FEX), cetirizine (CET), propranolol (PRP), dextromethorphan (DEX), norfloxacin (NOR), ofloxacin (OFL) and HCZ were used for the initial comparison. Photochemical oxidation was performed on‐chip and the CL conditions were selected based on our previous work . For chemical oxidation, an offline procedure was undertaken initially with Ce(IV) to understand the suitability of oxidant with selected compounds.…”

“…This is because of relatively high mixing efficiency and reproducibility. Our group have been extensively studying the applications of a MF‐CL detector for quantitative analysis of pharmaceutical formulations and biological samples by combining it with flow injection, capillary HPLC and micellar liquid chromatography…”

“…In this study an on‐chip in situ chemical oxidation procedure was developed for constant and instant delivery of the fresh Ru(bipy) 3 3+ reagent. Among the various on‐chip oxidation methods reported so far, photochemical and electrochemical methods have been used more frequently. A limited amount of work has been done on utilising the on‐chip chemical oxidation of Ru(bipy) 3 2+ but these procedures are not fully comparable with the concept of offline procedures .…”

Enhancing the chemiluminescence intensity of a KMnO4 formaldehyde system for estimating the total phenolic content in honey samples using a novel nanodroplet mixing approach in a microfluidics platform

“…The cost can be reduced significantly if a similar mixing efficiency can be achieved using a two‐layer design. Additionally, the size of the holes in the middle layer was very small and therefore the holes became prone to clogging and were difficult to clean …”

Microfluidics Group – Department of Chemistry, Sultan Qaboos University

“…Additionally, the grant helped a great deal in creating an excellent research environment and a strong research group. The microfluidics group presented a number of scientific papers at international conferences and published several papers in international journals (Talanta [ 1 , 2 ], Analytical Methods [ 3 ] and Luminescence [ 4 , 5 ]). Additionally, we participated in the Oman innovation fair in 2011 and received an award for the best innovation at the exhibition.…”