Background: Data on timing of complications are important for accurate quality assessments. We sought to better define pre-and postdischarge complications occurring within 90 days of adult spinal deformity (ASD) surgery and quantify the effect of multiple complications on recovery. Methods: We performed a review of 1040 patients who underwent ASD surgery (age: 46 6 23; body mass index: 25 6 7, American Society of Anesthesiologists [ASA] score: 2.5 6 0.6, levels: 10 6 4, revision: 9%, 3-column osteotomy: 13%). We assessed pre-and postdischarge complications and risk factors for isolated versus multiple complications, as well as the impact of multiple complications. Results: The 90-day complication rate was 17.7%. 85 patients (8.2%) developed a predischarge complication, most commonly ileus (12%), and pulmonary embolism (PE; 7.1%). The most common causes of predischarge unplanned reoperation were neurologic injury (12.9%) and surgical site drainage (8.2%). Predictors of a predischarge complication included smoking (odds ratio [OR]:2.2, P ¼ .02), higher ASA (OR:1.8, P ¼ .008), hypertension (HTN; OR:2.0, P ¼ .004), and iliac fixation (OR: 4.3, P , .001). Ninety-nine patients (9.5%) developed a postdischarge complication, most commonly infection (34%), instrumentation failure (13.4%), and proximal junctional failure (10.4%). Predictors of postdischarge complications included chronic obstructive pulmonary disease (OR: 3.6, P , .0001), congestive heart failure (OR: 4.4, P ¼ .016), HTN (OR: 2.3, P , .0001), and multiple rod construct (OR: 1.8, P ¼ .02). Patients who developed multiple complications (9.3%) had a longer length of stay, and increased risk for readmission and unplanned reoperation. Conclusions: Knowledge regarding timing of postoperative complications in relation to discharge may better inform quality improvement measures. PE and implant-related complications play a prominent role in perioperative complications and need for readmission, with several modifiable risk factors identified.