Analysis of price variation amongst different formulations of anxiolytic drugs available in Indian market

Chawan, Vihang S.; Badwane, Sagar V.; Gawand, Kalpesh V.; Chhaya, Maheshi U.

doi:10.18203/2320-6012.ijrms20161821

Cited by 7 publications

(7 citation statements)

References 7 publications

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“…The findings are in line with other similar studies on various anticoagulants, antiplatelets, and fibrinolytics [14,15]. Besides, such cost variations have been observed previously among other groups of drugs as well [16][17][18]. All of these serve as evidence to formulate stringent and regularized drug-pricing policies in the nation.…”

Section: Discussionsupporting

confidence: 90%

A Cost Variation Analysis of Drugs Available in the Indian Market for the Management of Thromboembolic Disorders

Ray¹,

Najmi²,

Khandelwal³

et al. 2020

Cureus

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Introduction Cardiovascular diseases (CVDs) have become one of the major causes of mortality among the Indian population. The costs of anticoagulant, antiplatelet, and fibrinolytic drugs that are used to treat various thromboembolic disorders and used as prophylactics for individuals at high risk of CVDs vary widely in the Indian pharmaceutical market. The aim of this study was to evaluate the cost variation of different brands of drug formulations and to compare the branded prices of the formulations with their corresponding generic and ceiling prices. Materials and methods This study followed an analytical method. Costs of various drugs were obtained from the October-December 2019 edition of the Current Index of Medical Specialities (CIMS) and December 2019 edition of the Monthly Index of Medical Specialities (MIMS) India. Cost ratio and percentage variation in cost per tablet/capsule/injection of different drugs available in the Indian market and manufactured by different pharmaceutical companies were calculated. Comparison of the branded prices with generic and ceiling prices was also performed for different drugs by using information available from official websites. Results Percentage variation in cost among the commonly prescribed drugs for the management of thromboembolic disorders was found to be highest for prasugrel 10 mg tablet (1,408.44%) while it was lowest for fondaparinux 2.5 mg / 0.5 ml injection (20%). Among the commonly prescribed drugs that are under Drugs Prices Control Order (DPCO) price control, streptokinase 1.5 MIU injection had the highest cost variation (132.02%) while enoxaparin 60 mg / 0.6 ml injection had the lowest (4.99%). Among some of the important formulations under the Jan Aushadhi scheme (JAS), acenocoumarol 2 mg tablet had the highest cost variation (680.09%) and cilostazol 50 mg tablet had the lowest (55.46%). Conclusions Wide differences exist in the costs of various anticoagulants, antiplatelets, and fibrinolytics available in the Indian market. The prescribing physician should be aware of theses variations and prescribe medicines accordingly, keeping in mind the financial status of the patients.

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Section: Discussionsupporting

confidence: 90%

A Cost Variation Analysis of Drugs Available in the Indian Market for the Management of Thromboembolic Disorders

Ray¹,

Najmi²,

Khandelwal³

et al. 2020

Cureus

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“…Similar type of price variability is found in another study by Tiwari and Yadav [8]. Not only in the oral antidiabetic agents but also such high price variation is also found in another group of drugs such as drugs used for coagulation disorders, antihypertensive, anxiolytics, hypolipidemics, and nonsteroidal anti-inflammatory drugs in Indian market [1,[9][10][11][12]. Hence, from all these studies, we come to know that in India a strict policy must require to control high price variation by different companies.…”

Section: Discussionsupporting

confidence: 70%

Oral Antidiabetics Agents Available in Indian Pharmaceutical Market: A Price Variation Analysis

Thacker

Mistry

Kanani

2020

Asian J Pharm Clin Res

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Objective: There are hundreds of brands in Indian markets for a single drug which is manufactured by various companies and thus leads to wide variation in prices for the same drug. Hence, we decide to evaluate the variation in price of different brands of the same drug available in Indian market. Methods: An analysis was done for comparing price variations among various drugs prescribed in diabetes mellitus. Indian Drug Review (IDR) (2019 Volume XXV Issue 4) and Current Index of Medical Specialties (CIMS) (July 2019–October 2019) were referred to know the maximum and minimum price in INR of drugs in all available strength and dosage forms being manufactured by different companies in India and percentage price variation was calculated. Results: Wide variation in the price of several brands of oral antidiabetics is found in Indian market. In single drug, highest price variation is found for glimepiride 1 mg tablet (1365.5%). In fixed-dose combinations (FDCs), highest price variation is found for glimepiride + metformin (2 mg + 500 mg) sustain release tablet (689.2%). Lowest price variation for FDCs was found for glimepiride + metformin (3 mg + 500 mg) tablet (4.8%). Furthermore, only few oral antidiabetic agents were included in the drug pricing control order 2013. Wide variation is seen in prices of brand and generic medicines. Conclusion: All the stakeholders should collectively make efforts to reduce price variation among the various brands so as to make them affordable and aim to improve the health status of the community.

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“…10,11 Some previous price analysis studies of oral hypolipidemic drugs, antiepileptic drugs, oral fluoroquinolone antibiotics and anxiolytic drugs have also showed such a wide variation in prices in Indian market. [12][13][14][15] This study also highlights the wide variation in prices amongst antianginal drugs marketed in India.…”

Section: Discussionmentioning

confidence: 61%

Price analysis of antianginal drugs available in Indian market

Chawan

Badwane

Gawand

et al. 2016

Int J Basic Clin Pharmacol

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Analysis of price variation amongst different formulations of anxiolytic drugs available in Indian market

Cited by 7 publications

References 7 publications

A Cost Variation Analysis of Drugs Available in the Indian Market for the Management of Thromboembolic Disorders

A Cost Variation Analysis of Drugs Available in the Indian Market for the Management of Thromboembolic Disorders

Oral Antidiabetics Agents Available in Indian Pharmaceutical Market: A Price Variation Analysis

Price analysis of antianginal drugs available in Indian market

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