Many cities in China have opened a subway, which has become an important part of urban public transport. How the metro line forms the metro network, and then changes the urban traffic pattern, is a problem worthy of attention. From 2005 to 2018, 10 metro lines were opened in Nanjing, which provides important reference data for the study of the spatial and temporal evolution of the Metro network. In this study, using the complex network method, according to the opening sequence of 10 metro lines in Nanjing, space L and space P models are established, respectively. In view of the evolution of metro network parameters, four parameters—network density, network centrality, network clustering coefficient, and network average distance—are proposed for evaluation. In view of the spatial structure change of the metro network, this study combines the concept of node degree in a complex network, analyzes the starting point, terminal point, and intersection point of metro line, and puts forward the concepts of star structure and ring structure. The analysis of the space‒time evolution of Nanjing metro network shows that with the gradual opening of metro lines, the metro network presents a more complex structure; the line connection tends to important nodes, and gradually outlines the city’s commercial space pattern.