Analysis of Resistance to Antibiotics of Pathogens of Ent Bacterial Infections

Abstract

Objective: to study the dynamics of the detection of resistance to antibiotics of the infectious agents of the ENT organs in 2011 and 2016. Material and methods. The study of the sensitivity of microflora to antibiotics was performed by the diffusion method in agar (standard disk method) in accordance with the Order of the Ministry of Health of Ukraine No. 167 dated 05.04.2007. Results. The study has found growth of the resistance of the bacterial flora isolated from the ENT organs to some fluoroquinolones (norfloxacin, ciprofloxacin, levofloxacin), aminopenicillins (ampicillin, amoxicillin), macrolides (azithromycin) maintaining its sensitivity to meropenem, tygecycline and cephalosporins, especially to cephoperazone, ceftriaxone, and cephepime. Conclusion. Active antibiotic therapy over the past five years has led to a sharp decrease in the sensitivity of the pathogens of ENT infectious diseases to traditional drugs used for empirical therapy. It is necessary to monitor the sensitivity of microorganisms to antibiotics in each region in order to determine the tendency of resistance of the leading etiological agents to antibiotics.