The present research focuses on the optimization of wire-cut electric discharge machining (WEDM) parameters. In this study, RSM based multi-response desirability method is used to optimize the WEDM characteristics for single and multiple responses. Input parameters of WEDM viz. pulse-on time, pulseoff time, spark gap voltage, wire tension, peak current, wire feed and performance was measured in terms of material removal rate (MRR) and surface roughness (SR). WEDM is a nontraditional method uses the spark erosion principle to produce the intricate shape and profiles of difficult-to-cut material. Inconel 825 is increasing in demand in the aerospace industry for more heat resistant and tough material. Because of its robust nature, it is difficult to be machined with conventional methods. WEDM is best alternate to overcome this problem. It has been observed that at Ton 111 MU, Toff 35 MU, SV 46V, IP 140A, WT 9 MU and WF 6 m/min, the values obtained for MRR and SR are 32.015mm2/min and 2.528 μm respectively.