Analysis of results of soft tissue sarcoma margins revision surgery

García-Jiménez, Antonio; Trullols-Tarragó, L.; Peiró-Ibáñez, A.; Gracia-Alegría, I

doi:10.1016/j.recote.2016.09.008

Cited by 1 publication

(2 citation statements)

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“…Inexperienced practitioners may have an R2 rate of up to 13.5% [ 15 ]. However, after inappropriate surgery, imaging studies indicated the presence of residual disease in 53.1% of patients [ 19 ]. It is important to note that this study did not provide information on the radicality of the primary surgery.…”

Section: Incidencementioning

confidence: 99%

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What is the Optimal Treatment Strategy after Sarcoma R2 Surgery?

Chmiel,

Rutkowski,

Spałek

et al. 2024

Curr. Treat. Options in Oncol.

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Opinion statementSoft tissue sarcomas (STS) are rare tumours of mesenchymal origin, most commonly occurring in the extremity but also in the retroperitoneum. The curative treatment for STS is radical surgery with wide margins, in some cases in combination with perioperative radiotherapy and chemotherapy. Nonradical resection (R2) of STS has been an emerging issue in recent decades, as optimal subsequent management remains debatable. Similarly, there is still no consensus on optimal surgical margins. Combining multiple treatment modalities in adjuvant therapy can achieve local and distant control in patients following surgery with positive margins. Patients who have undergone nonradical resection therefore require additional surgical interventions, and adjuvant radiotherapy resulting in a better prognosis but a higher number of complications. Following non-radical treatment, patients with limb and trunk wall sarcomas and retroperitoneal sarcomas should also undergo increased oncological surveillance. Given the potential issues that may emerge in such clinical situations, it is crucial to up-date the current guidelines to enhance the long-term prognosis of these patients.

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Section: Incidencementioning

confidence: 99%

“…The critical role of achieving negative surgical margins to optimize local management of STS is widely recognized. Positive surgical margins predict local recurrence (LR) following STS excision [ 18 , 19 ]. Although not universally, numerous studies have also linked LR with a reduction in overall survival (OS) [ 20 , 21 ].…”

Section: Introductionmentioning

confidence: 99%