Analysis of risk factors associated to cytomegalovirus infection in dentistry students.

Tejera-Hernández, Claudia De la; Noyola, Daniel E.; Sánchez-Vargas, Luis Octavio; Nava-Zárate, Nadya; Cruz-Mendoza, Esperanza de la; Gómez-Hernández, Araceli; Aranda‐Romo, Saray

doi:10.17126/joralres.2015.039

Cited by 3 publications

(3 citation statements)

References 19 publications

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“…3 ) [ 52 , 53 ]. LATAM and North America had notable differences in seroprevalence, with ranges of 59.1 to 91.3% [ 42 , 44 , 54 , 55 ] and 33.0 to 81.0% [ 33 , 45 – 47 ], respectively. Comparing the range maximums, Europe appeared to have the highest seroprevalence of CMV among adults.…”

Section: Seroprevalence By Sex and Age Groupmentioning

confidence: 99%

“…CMV IgG seroprevalence was higher among developing than developed countries included in this report. Among adults, CMV IgG seroprevalence ranged from 33.0 to 81.0% for developed countries [ 32 , 33 , 36 , 45 – 50 , 52 , 53 ] and 59.1 to 95.7% for developing countries [ 35 , 37 , 40 , 42 , 44 , 51 , 54 , 55 ]. For the elderly, seroprevalence was 64.5 to 96.2% for developed countries [ 56 , 57 ] and 93.8 to 97.7% for developing countries [ 35 , 51 ].…”

Section: Seroprevalence By Sex and Age Groupmentioning

confidence: 99%

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A systematic literature review of the global seroprevalence of cytomegalovirus: possible implications for treatment, screening, and vaccine development

Fowler

Mucha²,

Neumann³

et al. 2022

BMC Public Health

112

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Background Cytomegalovirus (CMV) is a common pathogen that affects individuals of all ages and establishes lifelong latency. Although CMV is typically asymptomatic in healthy individuals, infection during pregnancy or in immunocompromised individuals can cause severe disease. Currently, treatments are limited, with no prophylactic vaccine available. Knowledge of the current epidemiologic burden of CMV is necessary to understand the need for treatment and prevention. A systematic literature review (SLR) was conducted to describe the most recent epidemiologic burden of CMV globally. Methods Medline, Embase, and LILACS were searched to identify data on CMV prevalence, seroprevalence, shedding, and transmission rates. The SLR covered the time period of 2010–2020 and focused geographically on Australia, Europe, Israel, Japan, Latin America (LATAM), and North America. Studies were excluded if they were systematic or narrative reviews, abstracts, case series, letters, or correspondence. Studies with sample sizes < 100 were excluded to focus on studies with higher quality of data. Results Twenty-nine studies were included. Among adult men, CMV immunoglobulin G (IgG) seroprevalence ranged from 39.3% (France) to 48.0% (United States). Among women of reproductive age in Europe, Japan, LATAM, and North America, CMV IgG seroprevalence was 45.6-95.7%, 60.2%, 58.3-94.5%, and 24.6-81.0%, respectively. Seroprevalence increased with age and was lower in developed than developing countries, but data were limited. No studies of CMV immunoglobulin M (IgM) seroprevalence among men were identified. Among women of reproductive age, CMV IgM seroprevalence was heterogenous across Europe (1.0-4.6%), North America (2.3-4.5%), Japan (0.8%), and LATAM (0-0.7%). CMV seroprevalence correlated with race, ethnicity, socioeconomic status, and education level. CMV shedding ranged between 0% and 70.2% depending on age group. No findings on CMV transmission rates were identified. Conclusions Certain populations and regions are at a substantially higher risk of CMV infection. The extensive epidemiologic burden of CMV calls for increased efforts in the research and development of vaccines and treatments. Trial registration N/A.

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Section: Seroprevalence By Sex and Age Groupmentioning

confidence: 99%

Section: Seroprevalence By Sex and Age Groupmentioning

confidence: 99%

A systematic literature review of the global seroprevalence of cytomegalovirus: possible implications for treatment, screening, and vaccine development

Fowler

Mucha²,

Neumann³

et al. 2022

BMC Public Health

112

View full text Add to dashboard Cite

show abstract

“…The eyes are at particular risk from floating particles, which are considered serious hazards for DHCW, because they can transmit various microorganisms, e.g., cytomegalovirus, Mycobacterium tuberculosis , hepatitis B and hepatitis C viruses (HBV and HCV), Herpes simplex virus type 1, human immunodeficiency virus (HIV), streptococci, transmissible spongiform encephalopathies (including variant CJD), methicillin-resistant Staphylococcus aureus (MRSA), and severe acute respiratory syndrome (SARS) virus transmitted through direct and indirect contact [1], [2], [3], [4], [5], [6], [7], [8], [9], [10], [11], [12], [13], [14], [15], [16], [17]. …”

Section: Introductionmentioning

confidence: 99%

Awareness and compliance of dental students and interns toward infection control at Riyadh Elm University

Binalrimal

AlDrees²,

AlWehaibi³

et al. 2019

GMS Hygiene and Infection Control; 14:Doc10

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Assessment of NKG2C copy number variation in HIV-1 infection susceptibility, and considerations about the potential role of lacking receptors and virus infection

et al. 2022

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Human Immunodeficiency Virus (HIV) infection dynamics is strongly influenced by the host genetic background. NKG2C is an activating receptor expressed mainly on Natural Killer (NK) cells, and a polymorphism of copy number variation in the gene coding for this molecule has been pointed as a potential factor involved in HIV infection susceptibility. We evaluated the impact of the NKG2C deletion on HIV-1 susceptibility, with or without HBV/HCV co-infection, in a total of 780 individuals, including 385 HIV-infected patients and 395 healthy blood donors. NKG2C deletion genotyping was performed by standard PCR. To our knowledge, this is the first study to access the impact of complete NKG2C deletion among HIV-infected Brazilian individuals. The frequency of NKG2C deletion (range: 19–22%) was similar in cases and controls. No association of NKG2C deletion with HIV-1 susceptibility or influence on clinical features, HBV or HCV co-infection was observed in the evaluated population. Our findings suggest that NKG2C deletion, and the consequent absence of this receptor expression, does not directly impact HIV susceptibility, HBV/HCV-co-infection in the studied population, suggesting that other signaling pathways might be triggered and perform similar functions in cell activity in the absence of this specific receptor, preventing the development of disadvantageous phenotypes. Larger cohorts and studies involving protein expression are necessary to confirm our findings.

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Analysis of risk factors associated to cytomegalovirus infection in dentistry students.

Cited by 3 publications

References 19 publications

A systematic literature review of the global seroprevalence of cytomegalovirus: possible implications for treatment, screening, and vaccine development

A systematic literature review of the global seroprevalence of cytomegalovirus: possible implications for treatment, screening, and vaccine development

Awareness and compliance of dental students and interns toward infection control at Riyadh Elm University

Assessment of NKG2C copy number variation in HIV-1 infection susceptibility, and considerations about the potential role of lacking receptors and virus infection

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