Analysis of sulfamethoxazole by square wave voltammetry using new carbon paste electrode

Abstract

<p class="PaperAbstract"><span lang="EN-US">In this work a new model of carbon paste electrode was employed to determine sulfamethoxazole (SMX), an antibiotic used to treat infections in human and veterinary medicine, by the square wave voltammetric modality (SWV). More specifically, the elec­trochemical behavior of SMX was investigated by cyclic voltammetry (CV), and the quantitative analysis of SMX was provided by SWV. The analytical curve was obtained with a linear correlation coefficient (r) of 0.985 and standard deviation (SD) of 0.005 μA. Limits of detection and quantification were found as 2.3</span><a name="_Hlk512068463"></a><span lang="EN-US">×</span><span lang="EN-US">10<sup>-6</sup> and 7.7</span><span lang="EN-US">×</span><span lang="EN-US">10<sup>-6</sup> mol L<sup>-1</sup>, respectively. According to the obtained results, the new carbon paste prototype electrode can successfully be employed in this kind of electroanalytical applications.</span></p>

Determination of Solubility of 4-(2-Hydroxyethyl)-1-piperazineethanesulfonic Acid and its Sodium Salt in Acetonitrile and Voltammetric Investigation of Sulphonamide Drugs in Different Solvents in Their Absence and Presence

“…Therefore many analytical procedures have been developed for sulphonamide drugs to detect them in blood plasma. In the majority of electrochemical investigations glassy carbon and carbon based electrodes are used with and without modifying layer [7][8][9][10][11][12][13][14][15][16][17] but some works utilize the mercury electrode in electroreduction processes [18,19]. Regarding the direct electrochemical reaction of sulphonamides no work is found in the literature where platinum electrode acted as working electrode.…”