Analysis of Survival and Toxicity of Elderly Patients of Head and Neck Squamous Cell Carcinoma Treated With Induction Chemotherapy Followed By Definitive Radiation Therapy

Abstract

to the submandibular gland with hydrogel spacing was noted in the specimen with the smallest baseline gland volume. Conclusion: Injection of biodegradable radiopaque hydrogel successfully displaces the contralateral submandibular gland, providing the opportunity for dosimetrically sparing the gland. This minimally invasive technique should be tested in a clinical trial for reduction of xerostomia.

Factors Influencing Treatment Outcome of Non-Nasopharyngeal Head and Neck Squamous Cell Carcinoma in Geriatric Patients

“…In our present study, no difference was detected in DFS with or without associated co-morbidities. Our results are similar to those reported by Rastogi et al 20 who studied the treatment outcome of HNSCC geriatric patients (>70 years). In their study, no correlation between co-morbidities and DFS was observed.…”

“…In our study, the three years DFS was numerically lower for patients who had PS II and III (54%) compared to patients had PS I (78.7%) but no statistical significance was found (P=0.56). similarly, there was no correlation between DFS and PS status in HNSCC geriatric patients (>70 years) was detected in the study performed by Rastogi et al 20 .…”

“…In our study, 3years OS was 53.2% for all patients, which is lower than the reported survival of similar groups in the SEER database; but when compared to an Egyptian retrospective study at Clinical Oncology Department, Menoufia University 19 , the median OS for HNC was 24 months for patients > 60 years while in our study the median was not reached. Rastogi et al 20 studied the treatment outcome of HNSCC elderly patients (>70 years). The median DFS was 26.8 months and the 2 years DFS rate was 83.1%.…”