Analysis of the Association of Polymorphic Loci rs917997 in IL18RAP Gene and rs187238 in IL18 Gene with the Risk for Non-Hodgkin’s Malignant Lymphomas in Novosibirsk Population

Abstract

We analyzed the association of polymorphic variants of rs917997 (G/A) locus in IL18RAP gene and rs187238 (G/C) locus in IL18 gene with the risk of malignant non-Hodgkin's lymphomas in Novosibirsk population. Allele and genotype frequencies of the above loci were determined in patients (243 persons) and control group (371 persons) and compared using χ(2) test. None of the analyzed loci showed statistically significant association with the risk of malignant non-Hodgkin's lymphomas.