2021
DOI: 10.1136/ejhpharm-2021-002889
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Analysis of the clinical characteristics of dabigatran-induced oesophagitis

Abstract: Objectives Dabigatran-induced oesophagitis has emerged in recent years. However, the incidence and clinical characteristics of patients with dabigatran-induced oesophagitis have not yet been clarified. The aim of this study was to examine the clinical characteristics of the disease. Methods A retrospective analysis was undertaken of the literature on dabigatran-induced oesophagitis in Chinese and English from 2008 onwards. Results There were 20 men (74.07%) and seven women (25.93%) in the study; their median a… Show more

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Cited by 2 publications
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“…To reduce the risk of hemorrhage, our physicians prescribed 110 mg of dabigatran once or twice daily, based on evaluations 32 . Consistent with previous reports 33 35 , the preponderance of our endoscopic findings is indicative of esophagitis. Even though dabigatran was associated with the highest proportion and trend of UGIB events among NOAC users, the difference in cause‒effect occurrence was not statistically significant.…”
Section: Discussionsupporting
confidence: 93%
“…To reduce the risk of hemorrhage, our physicians prescribed 110 mg of dabigatran once or twice daily, based on evaluations 32 . Consistent with previous reports 33 35 , the preponderance of our endoscopic findings is indicative of esophagitis. Even though dabigatran was associated with the highest proportion and trend of UGIB events among NOAC users, the difference in cause‒effect occurrence was not statistically significant.…”
Section: Discussionsupporting
confidence: 93%