Cutting wood with circular saws is a popular machining operation in the woodworking and furniture industries. In the latter sliding table saws (panel saws) are commonly used for cutting of medium density fiberboards (MDF), high density fiberboards (HDF), laminate veneer lumber (LVL), plywood and chipboards of different structures. The most demanded requirements for machine tools are accuracy and precision, which mainly depend on the static deformation and dynamic behavior of the machine tool under variable cutting forces. The aim of this study is to present a new holistic approach in the process of changing the sliding table saw design solutions in order to obtain a better machine tool that can compete in the contemporary machine tool market. This study presents design variants of saw spindles, the changes that increase the critical speeds of spindles, the measurement results of the dynamic properties of the main drive system, as well as the development of the machine body structure. It was proved that the use of only rational imitation in the spindle design on the basis of the other sliding table saws produced does not lead to the expected effect in the form of correct spindle operation.