Chronic kidney disease is an urgent problem of childhood getting more and more interest on the one hand due to the higher incidence among children and the increased public health expenditures, and on the other hand due to the expanding opportunities for early diagnosis and prevention of the progression of this condition. Renoprotection means a set of measures of accompanying therapy that helps to preserve renal function, and in the case of advanced chronic renal failure — to maintain their residual function. The renoprotective strategy in children differs from that in adults, which is associated with the peculiarity of the causes of chronic kidney disease and the age-related characteristics of the physiology and pathology of body systems.